Background
The surgical management of acute Type A aortic dissection is evolving and many aortic centers of excellence are reporting superior outcomes. We hypothesize that similar trends exist in a multi-institutional regional consortium.
Methods
Records for 884 consecutive patients who underwent aortic operations (2003 to 2015) for acute Type A aortic dissection were extracted from a regional Society of Thoracic Surgeons database. Patients were stratified into three equal operative eras. Differences in outcomes and risk factors for morbidity and mortality were determined.
Results
Surgery for Type A aortic dissection is increasing in extent and complexity. Aortic root repair was performed in 16% of early era cases compared to 67% currently (p<0.0001). Similarly, aortic arch repair increased from 27% to 37% cases (p<0.0001). Cerebral perfusion is currently utilized in 85% of circulatory arrest cases, most frequently antegrade (57%). Total circulatory arrest times increased (29 vs 31 vs 36 min, p=0.005), but times without cerebral perfusion were stable (12 vs 6 min, p=0.68). While operative mortality remained stable at 18.9% during the 3 operative eras, there were significant decreases in pneumonia and reoperations (p<0.05). Predictors of operative mortality and major morbidity are age (OR=1.04; p<0.0001), prior stroke (OR=2.09; p=0.03), and elevated creatinine (OR 1.31, p=0.01). Importantly, extent of aortic operation did not increase risk for morbidity or mortality.
Conclusions
Operative morbidity and mortality remains significant for Type A aortic dissection, but lower than historical outcomes. Extent of aortic surgery has increased resulting in adaptive cerebral protection changes in contemporary “real-world” practice.