Differential associations of emotional and physical domains of the MacNew Heart with changes in 6-min walking test

Abstract

Aims Cardiac rehabilitation (CR), a key component of secondary prevention in cardiac patients, contributes fundamentally to improved cardiovascular health outcomes. Health-related quality of life (HRQOL) represents a widely employed outcome measure in CR, yet, its predictive properties on exercise capacity change during CR are poorly understood. Aim of this study was to examine the association between baseline HRQOL and its subdomains on improvement of exercise capacity during CR. Methods Study participants were 13,717 inpatients of six Swiss CR clinics from 2012 to 2018. We measured HRQOL at admission to CR with the MacNew Heart (MNH) questionnaire and exercise capacity at admission and discharge using the six minutes walking test (6MWT). Following factorial analyses, we performed univariate and multivariate analyses to test the predictive properties of baseline global HRQOL and its domains for improvement in exercise capacity, adjusting for demographic and clinical characteristics. Results Mean improvement in 6MWT was 114 m (SD = 90), achieved after 17.4 days (SD = 5.5). Lower emotional HRQOL (b = 7.85, p = < .001, 95% CI [− 5.67, 10.03]) and higher physical HRQOL (b = − 5.23, p < .001, 95% CI [− 6.56, − 3.90]) were associated with less improvement in the 6MWT. Global MNH and social HRQOL showed no association with exercise capacity improvement. Conclusion Patients entering CR with low emotional and high physical HRQOL are at risk for a lower gain in exercise capacity during CR. Global MNH alone does not provide a reliable assessment of HRQOL; thus a focus on specific domains of HRQOL is needed.

Relationship Between Functional Capacity and Health Related Quality of Life Among Cardiac Patients

“…Moreover, a prospective and an observational study revealed the strong impact of age, gender, residence, marital status, monthly income and clinical factors like comorbidities and number of hospitalizations on HRQOL and functional status of the patient. 15,20 An observational study conducted by Wu JR 13 and a cross-sectional study conducted by Jellestad L et al 21 and Wang G 15 concluded that the functional capacity is associated with the quality of life of patients who had undergone cardiac interventions. This is same as the results of present study.…”