Differential contributions of the anterior temporal and medial temporal lobe to the retrieval of memory for person identity information

Tsukiura, Takashi; Suzuki, Chisato; Shigemune, Yayoi; Mochizuki-Kawai, Hiroko

doi:10.1002/hbm.20469

Cited by 58 publications

(39 citation statements)

References 55 publications

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“…Impairments in recognising and naming famous people have been demonstrated in patients with temporal lobe lesions and following temporal lobe resection [4,10,45,46]. Famous faces have been shown to elicit activation in the anterior temporal lobes in functional imaging studies [3,11,35,42,47].…”

Section: Introductionmentioning

confidence: 99%

Famous People Knowledge and the Right and Left Temporal Lobes

Snowden

Thompson

Neary

2012

Behavioural Neurology

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Abstract. It is generally accepted that the anterior temporal lobes support knowledge of famous people. The specific roles of the right and left temporal lobe remain a subject of debate, with some studies suggesting differential roles based on modality (visual versus verbal information) and others category (person knowledge versus general semantics). The present study reexamined performance of semantic dementia patients with predominantly right and predominantly left temporal lobe atrophy on famous face, famous name and general semantic tasks, with the specific aim of testing the hypothesis that the right temporal lobe has a privileged role for person knowledge and the left temporal lobe for general semantic knowledge. Comparisons of performance rankings across tasks showed no evidence to support this hypothesis. By contrast, there was robust evidence from naming, identification and familiarity measures for modality effects: right-sided atrophy being associated with relatively greater impairment for faces and visual tasks and left-sided atrophy for names and verbal tasks. A double dissociation in test scores in two patients reinforced these findings. The data present a challenge for the influential 'semantic hub' model, which views the anterior temporal lobes as an area of convergence in which semantic information is represented in amodal form.

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Section: Introductionmentioning

confidence: 99%

Famous People Knowledge and the Right and Left Temporal Lobes

Snowden

Thompson

Neary

2012

Behavioural Neurology

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“…Next, we asked whether the ATL acts as a neural switchboard, performing in concert with other brain regions to enable the retrieval of different facets of person knowledge in a flexible and context-appropriate manner (study 2). We focus on the ATL because multiple lines of evidence from neuropsychology, electrophysiology, and neuroimaging have documented the critical role of the ATL in person identification (4, 5, 11-16), person-related learning (10,(17)(18)(19)(20)(21), semantic memory (6-8), and abstract social knowledge (1,(22)(23)(24)(25)(26)(27)(28)(29)(30)(31)(32)(33). Individuals with ATL damage due to resection or stroke have multimodal person recognition deficits (34), lose access to stored knowledge about familiar people (35,36), and have difficulties learning information about new people (4,22,37,38).…”

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confidence: 99%

Dynamic neural architecture for social knowledge retrieval

Wang

Collins

Koski

et al. 2017

Proc. Natl. Acad. Sci. U.S.A.

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Social behavior is often shaped by the rich storehouse of biographical information that we hold for other people. In our daily life, we rapidly and flexibly retrieve a host of biographical details about individuals in our social network, which often guide our decisions as we navigate complex social interactions. Even abstract traits associated with an individual, such as their political affiliation, can cue a rich cascade of person-specific knowledge. Here, we asked whether the anterior temporal lobe (ATL) serves as a hub for a distributed neural circuit that represents person knowledge. Fifty participants across two studies learned biographical information about fictitious people in a 2-d training paradigm. On day 3, they retrieved this biographical information while undergoing an fMRI scan. A series of multivariate and connectivity analyses suggest that the ATL stores abstract person identity representations. Moreover, this region coordinates interactions with a distributed network to support the flexible retrieval of person attributes. Together, our results suggest that the ATL is a central hub for representing and retrieving person knowledge.person knowledge | anterior temporal lobe | person identity node | semantic memory | social neuroscience A s social creatures, it is essential that we develop a rich storehouse of knowledge about other members of our social network, such as who they are, how they look and sound, where they live, and what they do for a living. However, little is known about how and where such "person knowledge" is represented, stored, and retrieved in the brain. This inquiry is challenging because person knowledge is highly multimodal and multifaceted, being linked to both abstract features such as personality and social status as well as more concrete features such as eye color; in addition, familiar individuals are associated with detailed episodic and semantic memories (e.g., memories of shared experiences and biographic information) (1, 2). The neural circuit for person knowledge must therefore have the ability to combine multiple sources of information into an abstract representation accessible from multiplicative cues.An influential theory by Burton and Bruce (3) proposes that person recognition is achieved through a hierarchical process that begins with the activation of modality-specific recognition units that selectively respond to the presence of a known face, name, or voice. This information is then sent to an amodal person identity node (PIN) that integrates information from the modality-specific recognition units into a multimodal representation for that individual. Excitation of the PIN ultimately allows the retrieval of personspecific semantic information independently of stimulus modality (4, 5). A similar design is embedded in the "hub-and-spoke" theory of semantic knowledge, which proposes that different features of a concept (such as its color or taste) are distributed throughout the brain (the "spokes") and that a centralized "hub" integrates these features into a cohe...

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“…In one hippocampal region (Fig. 4a), activity was enhanced for items attracting correct source judgments, regardless of the amount of contextual information (threshold-like effects; see also Tendolkar et al, 2008;Tsukiura et al, 2008). By contrast, in the other hippocampal region (Fig.…”

Section: Implications From Two Fmri Studiesmentioning

confidence: 93%

“…In a significant extension to this evidence, studies employing the extended source memory procedures listed in Table 1 show that there are two different patterns of hippocampal activity in response to recollection of source information. That is, one pattern of activity showed greater responses for accurate source judgments but no difference in response related to the amount of source information elicited by a test item (i.e., R=; threshold-like recollection effects; Suzuki et al, unpublished;Tendolkar et al, 2008;Tsukiura et al, 2008). By contrast, the other pattern of activity showed graded responses as a function of the amount of information recollected (R+; amount-sensitive recollection effects; Duarte et al, 2011;Mugikura et al, 2010;Suzuki et al, unpublished;Tendolkar et al, 2008;Yu et al, in press).…”

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confidence: 99%

Recollection of Episodic Memory and the Hippocampus: Evidence From Fmri

Suzuki

2012

PSYCHOLOGIA -An International Journal of Psychological Sciences

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Recognition memory is thought to be supported by two processes: the recollection of contextual information and an acontextual sense of familiarity from a previously experienced episode. There has been considerable interest in whether the hippocampus selectively supports recollection or whether the hippocampus contributes to both recollection and familiarity when memories are strong. Here, I briefly review results from event-related functional magnetic resonance imaging (fMRI) studies investigating the relationship between retrieval-related hippocampal activity and the recollection of contextual (source) information. On the basis of these findings, I argue that retrieval-related activity in the hippocampus is not modulated by differences in the undifferentiated memory strength elicited by test items. Instead, hippocampal activity is more likely to be sensitive to recollection success or to the amount of contextual information that is recollected in response to a test item.Key words: context memory, item memory, familiarity, memory strength, medial temporal lobeEpisodic memory is a neurocognitive system that enables individuals to consciously remember specific events and recall what happened where and when (Tulving, 1985a). It enables us to re-experience our past, live in the present, and imagine the future. As we all have experienced, memories of some events are more vivid and carry more detailed information than memories of other events. The difference between these memories is easily explained through the example of seeing a person at a party whom we have met previously. Sometimes we can easily remember contextual information about the person, such as his or her name or when and where we first met the person (i.e., recollection). On other occasions, however, despite recognizing the person as familiar, we are unable to recollect any contextual information about the person (i.e., familiarity). Such experiences suggest that recognition memory can be based on recollection and/or familiarity. Recollection involves the retrieval of specific details or information about a previously experienced episode, such as when or where an event occurred, whereas familiarity refers to an acontextual sense of awareness that an event has been experienced before in the

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Differential contributions of the anterior temporal and medial temporal lobe to the retrieval of memory for person identity information

Cited by 58 publications

References 55 publications

Famous People Knowledge and the Right and Left Temporal Lobes

Famous People Knowledge and the Right and Left Temporal Lobes

Dynamic neural architecture for social knowledge retrieval

Recollection of Episodic Memory and the Hippocampus: Evidence From Fmri

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