Differential Cross-Protective Immunity is Elicited by Infection with Contemporary Influenza B Lineage Viruses
Caroline Page,
Justin D. Shepard,
Sean D. Ray
et al.
Abstract:Influenza B virus (FLUBV) significantly contributes to the influenza disease burden and has complicated vaccine development and efficacy, yet remains understudied compared to its counterpart, influenza A virus (FLUAV). Since its isolation in 1940, FLUBV has diverged into two antigenically distinct lineages: Victoria (B/Vic) and Yamagata (B/Yam). Recent human studies and epidemiological modeling reveal differences in immunity elicited by each FLUBV lineage, contributing to higher reinfection rates following B/Y… Show more
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