Differential diagnosis of hypoalbuminemia in childhood: protein losing enteropathy associated to systemic lupus erythematosus in a young boy

Naddei, Roberta; Orlando, Francesca; Aloj, Giuseppina; Matteis, Arianna De; Alessio, Maria

doi:10.1097/meg.0000000000001480

Cited by 2 publications

(1 citation statement)

References 9 publications

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“…It is more frequent in females and Asiatic children and it can be the presenting manifestation or can occur during the SLE course, associated or not with other GI symptoms [93].…”

Section: Protein-losing Enteropathymentioning

confidence: 99%

Gastrointestinal Involvement in Children with Systemic Lupus Erythematosus

et al. 2023

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Systemic lupus erythematosus (SLE) is a systemic autoimmune disorder. When it presents before the age of 18 years (childhood-onset systemic lupus erythematosus, cSLE), the disease course tends to be more severe with a higher rate of organ involvement and requires an early diagnosis. Gastrointestinal involvement in cSLE is rare and scarcely reported in the literature. Any organ of the gastrointestinal system may be affected, either as a direct consequence of the disease, as a subsequent complication, or as an adverse drug event. Abdominal pain is the most common GI symptom, it can be diffuse or well localized, and can underline different conditions such as hepatitis, pancreatitis, appendicitis, peritonitis, or enteritis. cSLE may have an alteration of the intestinal barrier with features of protein-losing enteropathy or, in genetically predisposed patients, may develop associated autoimmune disorders such as Coeliac Disease or Autoimmune Hepatitis. The aim of this manuscript is to provide a narrative review of gastrointestinal manifestations in cSLE focused on hepatic, pancreatic, and intestinal involvement. A comprehensive literature search based on the PubMed database was performed.

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“…It is more frequent in females and Asiatic children and it can be the presenting manifestation or can occur during the SLE course, associated or not with other GI symptoms [93].…”

Section: Protein-losing Enteropathymentioning

confidence: 99%

Gastrointestinal Involvement in Children with Systemic Lupus Erythematosus

et al. 2023

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A case of systemic lupus erythematosus presenting with intestinal lymphangiectasia‐associated protein‐losing enteropathy accompanying hyperinflammation

2022

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Systemic lupus erythematosus (SLE) is an autoimmune disease which has many different manifestations including rash, arthritis, renal and neurological involvement. 1 SLE has the potential to affect virtually every organ; however, gastrointestinal system (GIS) manifestations are relatively rare compared to other autoimmune diseases such as systemic sclerosis and inflammatory bowel disease. On the other

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Differential diagnosis of hypoalbuminemia in childhood: protein losing enteropathy associated to systemic lupus erythematosus in a young boy

Cited by 2 publications

References 9 publications

Gastrointestinal Involvement in Children with Systemic Lupus Erythematosus

Gastrointestinal Involvement in Children with Systemic Lupus Erythematosus

A case of systemic lupus erythematosus presenting with intestinal lymphangiectasia‐associated protein‐losing enteropathy accompanying hyperinflammation

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