Differential Diagnosis of Jakob-Creutzfeldt Disease

The first reported case of Creutzfeldt‐Jakob disease from Nepal

“…She had no risk factors for vascular diseases. Cognition was not suddenly impaired as might be seen in strategic infarcts . Her coagulation profile was normal as well.…”

“…Because of its variable presentation, the diagnosis of CJD is challenging . Diagnostic criteria have been defined to identify this rare disorder.…”

Diagnostic challenge of non‐specific visual symptoms: consideration of Heidenhain variant of Creutzfeldt‐Jakob disease

“…Diagnosis of sporadic form of the CJD is a challenge because there is a great variability of the clinical manifestations, especially in early stages, that causes delayed diagnosis or misdiagnosis . Heidenhain's variant is even more challenging to diagnose during the early phase of the disease when there are only visual symptoms.…”

Probable Creutzfeldt Jakob Disease: Case Report

“…CJD is a rare neurological disorder with a prevalence of approximately 1 case per 1 million inhabitants, or approximately 1/10000 cases of Alzheimer's disease. Recently CJD caused alarm throughout Europe due to an epidemic of bovine spongiform encephalopathy (the "crazy cow" disease), this form being classified as variant CJD (Paterson et al, 2012). The variant CJD is more common in young adults, in contrast to the sporadic form that occurs commonly in patients over 50 years of age.…”

“…Patients with high hyper intense basal ganglia on T2 are more likely to present rapid progressive dementia in an initial stage and a shorter time span of the illness (average of 6.7 and 8.6 months). Depression and sensory disturbances are more frequent among cases without increased signs (Paterson et al, 2012).…”