“…6,7,10,15,20,25 In other cases, overt red flag findings were not evident; rather, a cluster of findings that were atypical for nonspecific low back pain emerged through the course of care that prompted referral. 3,6,8,14,15,21,27 Using a cluster of history and physical examination findings is also consistent with evidence-based screening strategies for serious conditions like cancer, 11 fractures, 17 and abdominal pain that is nonmusculoskeletal in nature. 24 For example, in an individual with low back pain, advanced age, corticosteroid use, or pain caused by a traumatic incident may not be concerning when each finding is considered in isolation.…”