2009
DOI: 10.1016/j.brainres.2008.12.047
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Differential distribution of neuregulin in human brain and spinal fluid

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Cited by 47 publications
(45 citation statements)
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References 53 publications
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“…This labeling paradigm allows highly labeled proteins synthesized over the first approximately 48-72 hours of label exposure to be monitored as they appear in and disappear from CSF ( Figure 1A). Cargo proteins were selected on the basis of the following published criteria: (a) high expression in neurons; (b) presence in CSF (Table 1); and (c) association with neurodegeneration and neuronal survival (11)(12)(13)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31).…”
Section: Altered Kinetics Of Neuronal Transport In Csf Of Murine Modementioning
confidence: 99%
See 1 more Smart Citation
“…This labeling paradigm allows highly labeled proteins synthesized over the first approximately 48-72 hours of label exposure to be monitored as they appear in and disappear from CSF ( Figure 1A). Cargo proteins were selected on the basis of the following published criteria: (a) high expression in neurons; (b) presence in CSF (Table 1); and (c) association with neurodegeneration and neuronal survival (11)(12)(13)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31).…”
Section: Altered Kinetics Of Neuronal Transport In Csf Of Murine Modementioning
confidence: 99%
“…CHGB and NRG1 have been linked to motoneuron degeneration and survival (25,26). CHGB, NRG1, sAPPα, and SNCA have been previously reported to be released extracellularly (22)(23)(24)(25)(28)(29)(30)(31).…”
Section: Figurementioning
confidence: 99%
“…This Iglike domain potentiates the biological activities of soluble NRG1 forms and leads to their highly selective tissue distributions through its affinity for specific cell-surface heparan sulfates (12,20,27,28). These forms are first expressed as transmembrane precursors (pro-NRG1) that undergo proteolytic cleavage to release their soluble ectodomains.…”
mentioning
confidence: 99%
“…Neuregulin-1s (NRG-1s) are a family of growth and differentiation factors with multiple roles in the development and function in the nervous system (Gajendran et al 2009;Pankonin et al 2009). NRG-1 is essential for myelination in the peripheral nervous system (Brinkmann et al 2008).…”
Section: Introductionmentioning
confidence: 99%