Differential effects of nasal continuous positive airway pressure on reversible or fixed upper and lower airway obstruction

Wang, Chun Hua; Lin, Horng Chyuan; Huang, Tiao‐Lai; Yang, Cheng‐Ta; Yu, Chih Teng; Kuo, H.P.

doi:10.1183/09031936.96.09050952

Cited by 20 publications

(9 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…There was a report that symptoms of extrathoracic airway obstruction such as stridor and dyspnea were significantly improved according to 20-30% increase of PIF in patients with reversible extrathoracic airway obstruction (22). Also, PIF is a very simple method to detect inspiratory flow limitation when a pattern of variable extrathoracic airway obstruction is observed in the flow-volume curve.…”

Section: Discussionmentioning

confidence: 99%

Cough Sensitivity and Extrathoracic Airway Responsiveness to Inhaled Capsaicin in Chronic Cough Patients

et al. 2002

View full text Add to dashboard Cite

Enhanced cough response has been frequently observed in chronic cough. Recently, extrathoracic airway constriction to inhaled histamine was demonstrated in some chronic cough patients. However, relation between extrathoracic airway hyperresponsiveness (EAHR) and cough sensitivity determined by capsaicin inhalation is unclear in each etiological entity of chronic cough. Seventy-seven patients, with dry cough persisting for 3 or more weeks, normal spirometry and chest radiography, and 15 controls, underwent methacholine bronchial provocation test and capsaicin cough provocation test. Elicited cough number and flow-volume curve was examined after inhalation of capsaicin to evaluate cough sensitivity and EAHR. Thirty-three patients, with postnasal drip, showed normal extrathoracic airway responsiveness, and 27 of them showed normal cough sensitivity to capsaicin. Cough sensitivity was enhanced in 14 patients with cough variant asthma (CVA) who showed bronchial hyperresponsiveness; EAHR to inhaled capsaicin was present in 12 of them. The remaining 30 patients were tentatively diagnosed as idiopathic chronic cough (ICC). Eleven ICC patients showed enhanced cough sensitivity and EAHR to inhaled capsaicin while 19 patients showed normal values. These results indicate that cough sensitivity is closely related with extrathoracic airway responsiveness during capsaicin provocation in some chronic cough patients. EAHR and enhanced cough sensitivity to inhaled capsaicin may be a part of mechanism developing chronic cough.

show abstract

Section: Discussionmentioning

confidence: 99%

Cough Sensitivity and Extrathoracic Airway Responsiveness to Inhaled Capsaicin in Chronic Cough Patients

et al. 2002

View full text Add to dashboard Cite

show abstract

“…Other authors have shown that nCPAP induces a decrease in the MEF 50 /MIF 50 ratio and an increase in PIF and forced inspiratory vital capacity, as well as a dramatic improvement of symptoms in patients with reversible upper airway obstruction due to vocal cord paralysis or edema [24]. …”

Section: Discussionmentioning

confidence: 99%

Myasthenic Inspiratory Vocal Cord Dysfunction: Efficacy of Nasal Continuous Positive Airway Pressure Treatment

Todisco¹,

Baglioni²,

Eslami³

et al. 2000

Respiration

View full text Add to dashboard Cite

Myasthenic vocal cord dysfunction (VCD), presenting with severe inspiratory stridor, was successfully treated with nasal continuous positive airway pressure (nCPAP), thus giving the medical staff time to make the diagnosis and avoiding intubation or tracheostomy. An important sign leading to diagnosis was the very high MEF₅₀/MIF₅₀ ratio calculated from the flow-volume loop. nCPAP treatment induced prompt remission of stridor and a sharp reduction in the MEF₅₀/MIF₅₀ ratio from 9.90 to 1.36. A review of the literature has shown that VCD with inspiratory stridor is an unusual onset symptom of myasthenia gravis and that nCPAP treatment may avoid emergency oral/tracheal intubation and tracheostomy. After diagnosis, the patient underwent thymectomy, and today, 3 years later, he is well without any further therapy.

show abstract

“…Positive pressure application may also prevent bronchospasm induced by various stimuli. Prior reports showed that methacholine and histamine induced bronchospasm could be averted by application of CPAP [41,42]. WILSON et al [43] have demonstrated that externally applied PEEP prevents exercise induced asthma.…”

Section: Effects Of and Rationale For Application Of Positive Pressurmentioning

confidence: 99%

Noninvasive positive pressure ventilation in acute asthmatic attack

Soroksky¹,

Klinowski²,

Ilgyev³

et al. 2010

Eur Respir Rev

View full text Add to dashboard Cite

Asthma is characterised by reversible airway obstruction. In most patients, control of disease activity is easily achieved. However, in a small minority, asthma may be fatal. Between the two extremes lie patients with severe asthmatic attacks, refractory to standard treatment. These patients are at an increased risk of recurrent severe attacks, with respiratory failure, and mechanical ventilation.Invasive mechanical ventilation of the asthmatic patient is associated with a higher risk of complications and, therefore, is a measure of last resort.Noninvasive positive pressure ventilation (NPPV) is another treatment modality that may be beneficial in patients with severe asthmatic attack who are at an increased risk of developing respiratory failure. These patients have the potential to benefit from early respiratory support in the form of NPPV. However, reports of NPPV in asthmatic patients are scarce, and its usage in asthmatic attacks is, therefore, still controversial. Only a few reports of NPPV in asthma have been published over the last decade. These studies mostly involve small numbers of patients and those who have problematic methodology.In this article we review the available evidence for NPPV in asthma and try to formulate our recommendations for NPPV application in asthma based on the available evidence and reports.

show abstract

Differential effects of nasal continuous positive airway pressure on reversible or fixed upper and lower airway obstruction

Cited by 20 publications

References 31 publications

Cough Sensitivity and Extrathoracic Airway Responsiveness to Inhaled Capsaicin in Chronic Cough Patients

Cough Sensitivity and Extrathoracic Airway Responsiveness to Inhaled Capsaicin in Chronic Cough Patients

Myasthenic Inspiratory Vocal Cord Dysfunction: Efficacy of Nasal Continuous Positive Airway Pressure Treatment

Noninvasive positive pressure ventilation in acute asthmatic attack

Contact Info

Product

Resources

About