Differential expression of flavonoid biosynthesis genes and biochemical composition in different tissues of pigmented and non-pigmented rice

Nayeem, Safia; Venkidasamy, Baskar; Sundararajan, Sathish; Kuppuraj, Sree Preethy

doi:10.1007/s13197-020-04602-3

Cited by 16 publications

(3 citation statements)

References 40 publications

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“…In addition, Nayeem et al, 2020 recently studied the expression of eight structural genes in purple rice cv. Navara and showed that the transcription levels of CHS, CHI, F3H, DFR, LAR and ANS were maximal in the root, while only PAL was found in the stem [ 95 ]. The differences in the expression levels among genes may be due to the presenting of the various colors occurring in plants throughout the plant life cycle.…”

Section: Anthocyanin Biosynthesis Genes In Regulation Of Anthocyanin In Ricementioning

confidence: 99%

The Potential of High-Anthocyanin Purple Rice as a Functional Ingredient in Human Health

Yamuangmorn

Prom‐u‐thai

2021

Antioxidants

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Purple rice is recognized as a source of natural anthocyanin compounds among health-conscious consumers who employ rice as their staple food. Anthocyanin is one of the major antioxidant compounds that protect against the reactive oxygen species (ROS) that cause cellular damage in plants and animals, including humans. The physiological role of anthocyanin in plants is not fully understood, but the benefits to human health are apparent against both chronic and non-chronic diseases. This review focuses on anthocyanin synthesis and accumulation in the whole plant of purple rice, from cultivation to the processed end products. The anthocyanin content in purple rice varies due to many factors, including genotype, cultivation, and management as well as post-harvest processing. The cultivation method strongly influences anthocyanin content in rice plants; water conditions, light quantity and quality, and available nutrients in the soil are important factors, while the low stability of anthocyanins means that they can be dramatically degraded under high-temperature conditions. The application of purple rice anthocyanins has been developed in both functional food and other purposes. To maximize the benefits of purple rice to human health, understanding the factors influencing anthocyanin synthesis and accumulation during the entire process from cultivation to product development can be a path for success.

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Section: Anthocyanin Biosynthesis Genes In Regulation Of Anthocyanin In Ricementioning

confidence: 99%

The Potential of High-Anthocyanin Purple Rice as a Functional Ingredient in Human Health

Yamuangmorn

Prom‐u‐thai

2021

Antioxidants

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“…Rice (Oryza sativa L.), the main staple food for more than 50% of the world's population, provides carbohydrates and protein to the average daily diet to supplement with essential micronutrients [10]. Recently, pigmented rice has received increasing attention due to its nutritional values and health benefits, which is in large conferred by its abundant content of phenolic compounds.…”

Section: Introductionmentioning

confidence: 99%

Stimulation of GLUT4 Glucose Uptake by Anthocyanin-Rich Extract from Black Rice (Oryza sativa L.) via PI3K/Akt and AMPK/p38 MAPK Signaling in C2C12 Cells

Feng

Chang

et al. 2022

Metabolites

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Anthocyanin from black rice was reported to have beneficial effects on diabetes, but the molecular mechanisms are still largely unknown. Black rice cultivated from different regions in Taiwan (Hualien and Changhua) were included in this study. Concentrations of anthocyanin were significantly higher using the ethanol extraction method than those using water; therefore, ethanol extracts from Hualien and Changhua black rice (HBRE and CBRE) were used for further investigation. 2-NBDG glucose uptake analysis revealed that both HBRE and CBRE promote glucose uptake in C2C12 myotubes. The membrane expression levels of GLUT4 and phosphorylation of IRS-1 also had been markedly increased by both HBRE and CBRE, which was in accordance with the glucose uptake results. CBRE did not affect the downstream of IRS-1 but significantly enhanced protein levels of p-AMPK/AMPK. In contrast, HBRE was shown to target various signaling participated in GLUT4 glucose uptake, including PI3K/Akt and the p38 MAPK/ERK. Overall, we demonstrated that anthocyanin-rich extracts from black rice stimulate GLUT4 glucose uptake via upregulation of PI3K/Akt and AMPK/p38 MAPK signaling in C2C12 myotubes. Our findings revealed that anthocyanin-rich black rice might be a promising functional food for the prevention and treatment of insulin resistance and diabetic hyperglycemia.

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“…The TFC of 905 accessions from the primary core collection in Yunnan province, China, was also identified [ 11 ]. In addition, the TFC of less than 20 Indian and South Korean rice varieties was identified [ 12 , 13 , 14 , 15 ]. Therefore, to identify germplasm rich in flavonoids, it is necessary to select more varieties with a wider geographical distribution and greater genetic variation.…”

Section: Introductionmentioning

confidence: 99%

Genome-Wide Association Study Reveals the Genetic Basis of Total Flavonoid Content in Brown Rice

Xia,

Pu,

Zhu

et al. 2023

Genes

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Flavonoids have anti-inflammatory, antioxidative, and anticarcinogenic effects. Breeding rice varieties rich in flavonoids can prevent chronic diseases such as cancer and cardio-cerebrovascular diseases. However, most of the genes reported are known to regulate flavonoid content in leaves or seedlings. To further elucidate the genetic basis of flavonoid content in rice grains and identify germplasm rich in flavonoids in grains, a set of rice core collections containing 633 accessions from 32 countries was used to determine total flavonoid content (TFC) in brown rice. We identified ten excellent germplasms with TFC exceeding 300 mg/100 g. Using a compressed mixed linear model, a total of 53 quantitative trait loci (QTLs) were detected through a genome-wide association study (GWAS). By combining linkage disequilibrium (LD) analysis, location of significant single nucleotide polymorphisms (SNPs), gene expression, and haplotype analysis, eight candidate genes were identified from two important QTLs (qTFC1-6 and qTFC9-7), among which LOC_Os01g59440 and LOC_Os09g24260 are the most likely candidate genes. We also analyzed the geographic distribution and breeding utilization of favorable haplotypes of the two genes. Our findings provide insights into the genetic basis of TFC in brown rice and could facilitate the breeding of flavonoid-rich varieties, which may be a prevention and adjuvant treatment for cancer and cardio-cerebrovascular diseases.

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Differential expression of flavonoid biosynthesis genes and biochemical composition in different tissues of pigmented and non-pigmented rice

Cited by 16 publications

References 40 publications

The Potential of High-Anthocyanin Purple Rice as a Functional Ingredient in Human Health

The Potential of High-Anthocyanin Purple Rice as a Functional Ingredient in Human Health

Stimulation of GLUT4 Glucose Uptake by Anthocyanin-Rich Extract from Black Rice (Oryza sativa L.) via PI3K/Akt and AMPK/p38 MAPK Signaling in C2C12 Cells

Genome-Wide Association Study Reveals the Genetic Basis of Total Flavonoid Content in Brown Rice

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