1998
DOI: 10.1006/bbrc.1998.9577
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Differential Expression of Rat Brain Bcl-2 Family Proteins in Development and Aging

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Cited by 61 publications
(26 citation statements)
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“…3 ). These trends are similar to work of other in- vestigators in whole brain evaluation of Bcl-2 family proteins in rats and mice [120][121][122] .…”
Section: Unique Features Of the Developing Brainsupporting
confidence: 85%
“…3 ). These trends are similar to work of other in- vestigators in whole brain evaluation of Bcl-2 family proteins in rats and mice [120][121][122] .…”
Section: Unique Features Of the Developing Brainsupporting
confidence: 85%
“…This importance is shown by the severe brainovergrowth malformations that occur in some strains of mice with complete absence of caspases 3 and 9 (Kuida et al, 1996, Kuida et al, 1998. Additional evidence that the neonatal brain has more abundant potential for activation of apoptosis pathways than the mature brain is that procaspase-3 is several times more abundant in the developing brain (Zhu et al, 2005) as are the proapoptosis members of the bcl 2 family (Shimohama et al, 1998).…”
Section: (Iv) Discussionmentioning
confidence: 99%
“…We have previously shown a differential and unique expression of apoptosis-regulating Bcl-2 family proteins in the rat brain during the course of development and aging (18). Although the biological meaning remains to be defined, it should be noted that the expression profile of caspase-3 and -7 is similar to that of Bax, Bak, and Bad, while that of caspase-8 and -10 is similar to that of Bcl-2.…”
Section: Figmentioning
confidence: 91%