1999
DOI: 10.1046/j.1440-1746.1999.01823.x
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Differential Helicobacter pylori infection rates in two contrasting gastric cancer risk regions of South China

Abstract: It is concluded that the prevalence of H. pylori infection rates bear a direct relationship to gastric cancer mortality rates in these two southern regions of China. Thus, H. pylori most likely plays a significant aetiopathogenetic role in gastric carcinogenesis in subjects living in Changle.

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Cited by 49 publications
(40 citation statements)
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References 30 publications
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“…The H. pylori prevalence previously reported in some parts of China was 46.8%-66.4% (13)(14)(15), reaching a maximum of 80.4% (16). In this study, the H. pylori prevalence in China was found to be significantly lower than that reported in previous studies (13)(14)(15)(16).…”
Section: Discussioncontrasting
confidence: 70%
See 1 more Smart Citation
“…The H. pylori prevalence previously reported in some parts of China was 46.8%-66.4% (13)(14)(15), reaching a maximum of 80.4% (16). In this study, the H. pylori prevalence in China was found to be significantly lower than that reported in previous studies (13)(14)(15)(16).…”
Section: Discussioncontrasting
confidence: 70%
“…The H. pylori prevalence previously reported in some parts of China was 46.8%-66.4% (13)(14)(15), reaching a maximum of 80.4% (16). In this study, the H. pylori prevalence in China was found to be significantly lower than that reported in previous studies (13)(14)(15)(16). This prevalence was consistent with those reported in some Western developed countries, and even it was surprisingly lower than those reported in some developed countries (17)(18)(19)(20) In recent years, the H. pylori prevalence has been decreasing in many areas of the world (22,23).…”
Section: Discussionmentioning
confidence: 88%
“…For instance, in China, the risk of gastric cancer in Changle, Fujian, was fivefold that of Hong Kong. (4) Muping County in Shandong, China also had a significantly higher risk of gastric cancer when compared to Yanqing County in Beijing. (5) Geographic variations in gastric cancer incidence and mortality in terms of a north-south gradient have been reported in both the West and the East.…”
Section: Epidemiological Trends In Gastric Cancermentioning
confidence: 99%
“…In Hong Kong, gastroesophageal reflux disease is getting more common with 3% to 7% of the population reporting heartburn or acid reflux equal or more than once weekly (8) and the prevalence of H. pylori has decreased from 58.4% in 1994 (9) to 50% in 1998 and 40% in 2002 (10). Hong Kong Chinese adopt a Westernized life-style.…”
Section: Introductionmentioning
confidence: 99%