Differential regulation of the translation and the stability of two maternal transcripts in preimplantation rabbit embryos

Henrion, Gwénola; Renard, Jean Paul; Chesné, P.; Oudin, Jean-Francois; Maniey, Dominique; Brunet, Adeline; Osborne, Howard Beverley; Duranthon, Véronique

doi:10.1002/(sici)1098-2795(200005)56:1<12::aid-mrd3>3.0.co;2-#

Cited by 18 publications

(3 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Egg activation also induces the destabilization of a subset of maternal transcripts. This phenomenon has been observed in a variety of model organisms such as mouse, rabbit, zebrafish, Xenopus , and Drosophila (Bachvarova and De Leon, 1980; Duval et al, 1990; Henrion et al, 1997, 2000; Bashirullah et al, 1999; Brunet‐Simon et al, 2001; Kishida and Callard, 2001).…”

Section: Posttranscriptional Control During Egg Activation and Early mentioning

confidence: 85%

Setting the stage for development: mRNA translation and stability during oocyte maturation and egg activation in Drosophila

Tadros

Lipshitz

2005

Developmental Dynamics

109

View full text Add to dashboard Cite

Early animal development is controlled by maternally encoded RNAs and proteins, which are loaded into the egg during oogenesis. Oocyte maturation and egg activation trigger changes in the translational status and the stability of specific maternal mRNAs. Whereas both maturation and activation have been studied in depth in amphibians and echinoderms, only recently have these processes begun to be dissected using the powerful genetic and molecular tools available in Drosophila. This review focuses on the mechanisms and functions of regulated maternal mRNA translation and stability in Drosophila-and compares these mechanisms with those elucidated in other animal models, particularly Xenopus-beginning late in oogenesis and continuing to the mid-blastula transition, when developmental control is transferred to zygotically synthesized transcripts. Developmental Dynamics 232:593-608, 2005.

show abstract

Section: Posttranscriptional Control During Egg Activation and Early mentioning

confidence: 85%

Setting the stage for development: mRNA translation and stability during oocyte maturation and egg activation in Drosophila

Tadros

Lipshitz

2005

Developmental Dynamics

109

View full text Add to dashboard Cite

show abstract

“…Therefore, all of the transcripts necessary to synthesize the proteins involved in the first zygotic cell divisions and those involved later in the maternal control of zygotic gene expression during MZT should be found in all stored maternal mRNAs [44][45][46]. In this context, the use of macroarrays is an efficient way to establish a quick overview of the expression map and to evaluate the presence of specific transcripts, as shown here for the GV oocyte.…”

Section: Discussionmentioning

confidence: 95%

Quantification of Cyclin B1 and p34cdc2 in Bovine Cumulus-Oocyte Complexes and Expression Mapping of Genes Involved in the Cell Cycle by Complementary DNA Macroarrays1

Robert

Hue

McGraw

et al. 2002

Biology of Reproduction

View full text Add to dashboard Cite

Although high amounts of cyclin B1 mRNA are present in bovine oocytes arrested at the germinal vesicle (GV) stage, the protein is not detectable. Furthermore, there is a depletion of the stored cyclin B1 mRNA in the oocyte as follicular growth progresses. To assess the effect of follicular growth on the accumulation of M-phase promoting factor (MPF) components, mRNA and protein levels of cyclin B1 and p34(cdc2) were measured in GV oocytes collected from diverse follicle size groups (<2 mm, 3-5 mm, and >6 mm). Because oocytes collected from very small follicles have high levels of cyclin B1 mRNA, the onset of its accumulation in the oocytes was evaluated by in situ hybridization of fetal ovaries. Also, a comparative expression map of cell cycle-related genes expressed in the oocyte and cumulus cells was established using nylon-based cDNA arrays, which allowed the detection of 35 different genes transcribed mostly in oocytes. Both components of the pre-MPF complex were expressed at the mRNA level in GV oocytes, whereas p34(cdc2) was the only pre-MPF protein detected at that stage, thus indicating that meiosis resumption in bovine oocytes is differentially regulated as compared with other mammals, and meiosis resumption seems to be regulated by the translation of cyclin B1 mRNA.

show abstract

“…Embryos not fused after 0.5–1 h of electrofusion were subjected to another round of the same treatment. The fused eggs were cultured in M16 solution containing 10% FCS, 2 m m glutamin, 2 m m penicillin G and 2 m m streptomycin in an atmosphere of 5% CO 2 at 38.5°C to the selected stage: 2‐cell‐stage, 4 h; 4‐cell‐stage, 6 h; 8–16‐cell‐stage, 30 h; and to a blastocyst, 78 h (Henrice et al . 2000; Zeng et al .…”

Section: Methodsmentioning

confidence: 99%

Analysis of gene expression in rabbit nuclear transfer embryos: Use of single‐embryo mRNA differential display

et al. 2003

Dev Growth Differ

View full text Add to dashboard Cite

Lack of or abnormal expression of developmentally important genes is believed to hamper early development of the nuclear transfer (NT) embryo. To identify stage-specific genes in rabbit NT embryo development, mRNA differential display was used to compare the mRNA content of rabbit NT embryos at different developmental stages, from Metaphase II oocytes to 8-16-cell stage embryos. Thirty-four zygotic transcripts, which abruptly appeared at the 8-16-cell stage in rabbit NT embryos, were isolated; 11 of these were potential novel genes with no matches in the current databases. Of the remaining 23, 12 were matched with established sequence tags with functions uncharacterized and the other 11 were homologous to those in the European Molecular Biology Laboratory (EMBL) and GenBank databases . The differential expression of eight of the 34 amplicons were confirmed by reverse Northern blotting, and four positive clones were validated. Previous studies and present data indicated that these three genes were probably related to preimplantation rabbit embryo development.

show abstract

Differential regulation of the translation and the stability of two maternal transcripts in preimplantation rabbit embryos

Cited by 18 publications

References 41 publications

Setting the stage for development: mRNA translation and stability during oocyte maturation and egg activation in Drosophila

Setting the stage for development: mRNA translation and stability during oocyte maturation and egg activation in Drosophila

Quantification of Cyclin B1 and p34cdc2 in Bovine Cumulus-Oocyte Complexes and Expression Mapping of Genes Involved in the Cell Cycle by Complementary DNA Macroarrays1

Analysis of gene expression in rabbit nuclear transfer embryos: Use of single‐embryo mRNA differential display

Contact Info

Product

Resources

About