Differential relationships of somatization, depression, and anxiety to severity of Crohn’s disease

Abstract

Patients with Crohn’s disease, an inflammatory bowel disease, struggle with chronic somatic symptoms that could bring about emotional distress. This study assessed the relative role of somatization, and depressive and anxiety symptoms in disease activity among 619 Crohn’s patients (18–79 years; 58.3% women). Structural equation modeling revealed that somatization was the only unique predictor of disease activity beyond depression and anxiety. In addition, the effect of somatization on disease activity was stronger in men compared to women. Findings suggest that somatization represents a distinct domain of psychological distress that may play a role in the health of patients with Crohn’s disease.

Randomized Controlled Trial of Cognitive-Behavioral and Mindfulness-Based Stress Reduction on the Quality of Life of Patients With Crohn Disease

“…The questionnaires are in the public domain, have validated Hebrew translations, and were used previously by patients with CD. 13,14,29 Participants provided information about sex, age, education, family status, religious observance, and economic status (self-rated on an arbitrary scale of 1 to 5, where 1 = poor and 5 = well-to-do).…”

“…9 Social dysfunction and isolation result. 10 Patients with CD suffer considerable psychological symptoms (anxiety, depression, somatization) during active and quiescent disease, [11][12][13][14][15][16] leading to a poor quality of life. [17][18][19] Mental fatigue also occurs frequently, 11 and it too is associated with a decreased quality of life.…”

“…Calprotectin: normal < 50 μg/g. SIBDQ: possible range 10-70, with emotional (3-21), physical(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14), bowel(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21), and social (2-14) domains. SF-12 PH: 0-100.…”

<p>The Relationship Between Symptoms of Anxiety and Somatic Symptoms in Health Professionals During the Coronavirus Disease 2019 Pandemic</p>

“…22 Regev et al reported that women showed higher psychological distress in somatic symptoms compared with men, but not in terms of depression and anxiety. 48 In addition, a previous study showed that women, the elderly, people with lower levels of education and family income, and fairly remote rural areas were more likely to be associated with somatic symptoms. 49 Taken together, these studies indicated that the consistent factor associated with somatic symptoms was gender.…”

Randomised clinical trial: Psychological intervention improves work productivity and daily activity by reducing abdominal pain and fatigue in Crohn's disease

“…The baseline construct validity of the abdominal pain measurement in our study was examined via cross-sectional correlations between abdominal pain composite score and a variety of physical and mental health key constructs previously found to be related to the CD illness experience. 25,33,34 Specifically, Pearson correlations were calculated at baseline between composite pain scores and measures of depression, anxiety and somatisation via three corresponding subscales of the Brief Symptom Inventory (BSI) 35 and modified measures of HBI, SF-12 and SIBDQ (excluding the relevant pain item from each scale). Correlations coefficients between abdominal pain and the three BSI subscales were statistically significant (all p < 0.001).…”