Differential Resting Quantitative Electroencephalographic Alpha Patterns in Women with Environmental Chemical Intolerance, Depressives, and Normals

Individual differences in neural sensitization and the role of context in illness from low-level environmental chemical exposures.

“…These observations include low rates of drug use and abuse despite elevated levels of affective distress (28). The partial limbic kindling and TDS model has a limited, but growing, amount of empirical evidence in humans (2,27,88,109) and in animals (34,44,45,62,63) to support its involvement in the multiple symptoms, phenomenology, and medical/psychiatric pictures of MCS patients (81). In particular, the sensitization model suggests specific experimental design considerations, without which one risks missing a true effect (type II error).…”

Multiweek Resting EEG Cordance Change Patterns from Repeated Olfactory Activation with Two Constitutionally Salient Homeopathic Remedies in Healthy Young Adults

“…The cutoff was determined using this sample but was similar to cutoffs in previously published samples. 42,44,45 The baseline cordance value was the first 5-minute cordance value obtained at visit 1 prior to performing the first sniff task or exposure to any remedy. Linear mixed models were also used to examine whether demographic characteristics (age, gender, CII group) and site (Fp1, Fp2) were associated with differences in baseline cordance values.…”

“…42 Previous research has shown that the CII identifies individuals who exhibit sensitization or oscillation of EEG responses to repeated exposures to the same agent over a several-week period. [43][44][45] Textbooks in homeopathy specifically identify persons with chemical sensitivity as ''universal provers'' with heightened reactivity to homeopathic remedies in general 30,46 and who are often clinically responsive to the class of remedies drawn from carbon-based sources, such as hydrocarbons or simple organic acids. 47 Exclusion criteria were pregnancy or planning to become pregnant, major psychiatric or serious medical conditions, chronic use of medications other than contraceptives, history of anaphylactic shock, asthma, and/or migraine headaches.…”

Asimetrías funcionales frontales en el trastorno depresivo mayor

“…Gotlib, Ranganath y Rosenfeld (27) replicaron independientemente las investigaciones iniciales en una muestra de 29 pacientes con TDM mostrando que la activación disminuida en regiones prefrontales izquierdas estaba fuertemente asociada con la vulnerabilidad al TDM. Del mismo modo, otros investigadores han obtenido resultados comparables utilizando esta aproximación (28)(29)(30) . Los estudios de EEG han sido complementados con otros cuyas tecnologías poseen mejor resolución espacial.…”