R evascularization procedures (percutaneous coronary intervention [PCI] and coronary bypass graft surgery [CABG]) are performed in more than 1.7 million patients with ischemic heart disease in the United States; more than 2.2 million PCIs alone are performed worldwide on an annual basis. 1 With technological advances in coronary intervention over the past 3 decades, procedural complications and longterm outcomes have significantly improved, yet periprocedural myocardial infarction (MI) remains common. We review the current state of knowledge of the incidence, risk factors, prognosis, and prevention of periprocedural MI after revascularization procedures, including PCI and CABG.