Differentiation of Crohn's disease and ulcerative colitis using intestinal wall thickness of the colon: A Diagnostic accuracy study of endoscopic ultrasonography

Roushan, Nader; Daryani, Nasser Ebrahimi; Azizi, Zahra; Pournaghshband, Helia; Niksirat, Ali

doi:10.47176/mjiri.33.57

Cited by 12 publications

(16 citation statements)

References 20 publications

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“…The imaging manifestations include abnormally increased thickness of the intestinal wall, abnormal hierarchical structure of the intestinal wall, and irregular or unclear boundaries between various layers of the intestinal wall. Some patients with UC have submucosal vasodilation and extraintestinal lymph node enlargement[ 15 , 16 ]. Other scholars have pointed out that through ultrasonic endoscopy, we can clearly evaluate the condition of the anal canal, terminal ileum, rectum, ileocecal valve, colon, and sigmoid colon with the help of enteroscopy, and we can perform cytological and pathological examination of potentially diseased regions[ 17 , 18 ].…”

Section: Discussionmentioning

confidence: 99%

Endoscopic ultrasonography in the evaluation of condition and prognosis of ulcerative colitis

Jin¹,

Chen²,

Chen³

et al. 2022

WJCC

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BACKGROUND Ulcerative colitis (UC) is usually diagnosed through histopathology, enteroscopy, clinical symptoms, and physical findings; however, it is difficult to accurately evaluate disease severity. AIM To investigate the value of endoscopic ultrasonography (EUS) in the evaluation of the severity and prognosis of UC. METHODS Patients with UC who were seen in our hospital from March 2019 to December 2020 were eligible, and disease severity was evaluated according to the modified Truelove and Witts and Mayo scores. We performed EUS, calculated the UC endoscopic index of severity (UCEIS) and EUS-UC scores, and administered appropriate treatment. The UCEIS and EUS-UC scores of patients were assessed in relation to disease severity, and the correlations between UCEIS and EUS-UC scores and disease severity was also analyzed. The UCEIS and EUS-UC scores before and after treatment were also compared. RESULTS A total of 79 patients were included in this study. According to the Mayo Index, 23, 32, and 24 patients had mild, moderate and severe UC, respectively. The UCEIS and EUS-UC scores were higher in moderate cases (4.98 ± 1.04 and 5.01 ± 0.99, respectively) than in mild cases (1.56 ± 0.82 and 1.64 ± 0.91, respectively, P < 0.05). Furthermore, the UCEIS and EUS-UC scores (7.31 ± 1.10 and 7.59 ± 1.02, respectively) were higher in severe cases than in moderate cases ( P < 0.05). According to the modified Truelove and Witts scores, 21, 36, and 22 patients were classified as having mild, moderate and severe disease, respectively. The UCEIS and EUS-UC scores were significantly higher in moderate disease (4.79 ± 1.11 and 4.96 ± 1.23, respectively) than in mild disease (1.71 ± 0.78 and 1.69 ± 0.88, respectively, P < 0.05). Additionally, the UCEIS and EUS-UC scores in severe disease (7.68 ± 1.22 and 7.81 ± 0.90, respectively) were significantly higher than in moderate disease ( P < 0.05). The UCEIS and EUS-UC scores were significantly and positively correlated with disease severity according to the modified Truelove and Witts score and Mayo score ( P < 0.05). The UCEIS and EUS-UC scores after 2 mo of treatment (3.88 ± 0.95 and 4.01 ± 1.14, respectively) and after 6 mo of treatment (1.59 ± 0.63 and 1.64 ± 0.59, respectively) were lower than the respective scores before treatment (5.93 ± 1.79 and 6.04 ± 2.01) ( P < 0.05). CONCLUSION EUS can clarify the status of UC and accurately evaluate the treatment response, providing an objective basis for formulation and adjustment of the treatment plan.

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Section: Discussionmentioning

confidence: 99%

Endoscopic ultrasonography in the evaluation of condition and prognosis of ulcerative colitis

Jin¹,

Chen²,

Chen³

et al. 2022

WJCC

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“…Endoscopic ultrasonography can be used as an efficient modality to differentiate between CD and UC and to evaluate the disease activity [ 49 ]. At this point, it is unclear whether the extension of endoscopic ultrasound diagnostics with elastography can affect the accuracy of this assessment.…”

Section: Discussionmentioning

confidence: 99%

Intestinal Elastography in the Diagnostics of Ulcerative Colitis: A Narrative Review

et al. 2022

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Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) that mainly affects developed countries, but the number of cases in developing countries is increasing. We conducted a narrative review on the potential application of ultrasound elastography in the diagnosis and monitoring of UC, as this newly emerging method has promising results in other gut diseases. This review fulfilled the PRISMA Statement criteria with a time cut-off of June 2022. At the end of the review, of the 1334 identified studies, only five fulfilled all the inclusion criteria. Due to the small number of studies in this field, a reliable assessment of the usefulness of ultrasound elastography is difficult. We can only conclude that the transabdominal elastography examination did not significantly differ from the standard gastrointestinal ultrasonography examination and that measurements of the frontal intestinal wall should be made in the longitudinal section. The reports suggest that it is impossible to estimate the clinical scales used in disease assessment solely on the basis of elastographic measurements. Due to the different inclusion criteria, measurement methodologies, and elastographic techniques used in the analysed studies, a reliable comparative evaluation was impossible. Further work is required to assess the validity of expanding gastrointestinal ultrasonography with elastography in the diagnosis and monitoring of UC.

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“…The inflammatory bowel diseases (IBD), colitis (UC) and Crohn's disease (CD) exhibit similar disease characteristics. However, with CD, inflammation is present along the lining of the digestive tract, whereas UC mediates inflammation in all aspects of the digestive tract and is primarily observed in the colon [1,2]. The global incidence of IBD is concerningly high, and expanding rapidly in developed nations [3].…”

Section: Introductionmentioning

confidence: 99%

Perceptions, beliefs and behaviors of nutritional and supplementary practices in inflammatory bowel disease

2022

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Purpose To gain insight into the behaviors, perceptions and beliefs of inflammatory bowel disease (IBD) patients nutritional and supplementary practices and also to explore perceptions and behaviors in relation to anti-inflammatory supplementation with specific emphasis on Montmorency tart cherries. Methods 80 IBD patients completed a 16-item close-ended questionnaire which was divided into three sub-sections: baseline/demographic characteristics, disease characteristics and dietary and supplementary perceptions, beliefs and behaviors. One-sample chi-square goodness of fit tests were used for each question and two-way Pearson chi-square tests of independence were used to undertake bivariate cross-tabulation comparisons to test differences in responses to each question between baseline/demographic variables. Results The majority of participants (N = 40) did not follow a specific dietary pattern or use supplements (N = 56). Respondents also predominantly rated that diet can both positively (N = 66) and negatively (N = 68) influence IBD. In addition, participants rated that supplements can positively influence IBD (N = 65) and that lack of scientific evidence was the primary mechanism preventing them from utilizing supplements (N = 34). Finally, patients also strongly reported that they would be willing to take Montmorency tart cherry supplementation (N = 73). Conclusions The disconnect between behavior and beliefs in both diet and supplementary practices, indicate that interventions designed to translate beliefs/knowledge into behaviors are warranted. There is also a necessity to undertake well-designed intervention trials examining the efficacy of food supplements, and with patient’s willingness to take Montmorency tart cherry, there is a strong rationale for future randomized trials examining the efficacy of tart cherry supplementation in IBD.

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Differentiation of Crohn's disease and ulcerative colitis using intestinal wall thickness of the colon: A Diagnostic accuracy study of endoscopic ultrasonography

Abstract: While there is no single standard method for diagnosing Ulcerative Colitis (UC) and Crohn's Disease (CD), ultrasonography (US) has been described as a non-invasive, less costly and efficient method that can be used for diagnosis and follow up of patients with IBD.

Cited by 12 publications

References 20 publications

Endoscopic ultrasonography in the evaluation of condition and prognosis of ulcerative colitis

Endoscopic ultrasonography in the evaluation of condition and prognosis of ulcerative colitis

Intestinal Elastography in the Diagnostics of Ulcerative Colitis: A Narrative Review

Perceptions, beliefs and behaviors of nutritional and supplementary practices in inflammatory bowel disease

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