Differentiation of the musculature of the teleost Brachydanio rerio

Raamsdonk, W. van; A, van der Stelt; Pc, Diegenbach; W, van de Berg; Bruyn, Helena De; J, van Dijk; Mijzen, P

doi:10.1007/bf00519641

Cited by 53 publications

(34 citation statements)

References 20 publications

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“…The development of this pattern occurs only after the embryos make their first movements. We found helical arrangements as early as 48·hpf, which is four days earlier than previously reported (Van Raamsdonk et al, 1974). As both wild-type and nic b107 embryos arranged their muscle fibres in helical patterns, it appears that the mechanical loading of the early parallel fibres is not necessary for the development of a helical pattern.…”

Section: Muscle Fibre Morphologysupporting

confidence: 43%

“…Fast fibres, which already form the bulk of the muscle mass, do not stain for heavy myosin chains until after 23·hpf (Devoto et al, 1996). Helical arrangements of zebrafish muscle fibres are first observed at 4·days after hatching (Van Raamsdonk et al, 1974). This timeline of development and use of the axial musculature also suggest that early use of the axial musculature is crucial for its proper development (Van Raamsdonk et al, 1977).…”

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confidence: 98%

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Effects of decreased muscle activity on developing axial musculature innicb107mutant zebrafish (Danio rerio)

Meulen

Schipper

Leeuwen

et al. 2005

Journal of Experimental Biology

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SUMMARY The present paper discusses the effects of decreased muscle activity (DMA)on embryonic development in the zebrafish. Wild-type zebrafish embryos become mobile around 18 h post-fertilisation, long before the axial musculature is fully differentiated. As a model for DMA, the nicb107mutant was used. In nicb107 mutant embryos, muscle fibres are mechanically intact and able to contract, but neuronal signalling is defective and the fibres are not activated, rendering the embryos immobile. Despite the immobility, distinguished slow and fast muscle fibres developed at the correct location in the axial muscles, helical muscle fibre arrangements were detected and sarcomere architecture was generated. However, in nicb107 mutant embryos the notochord is flatter and the cross-sectional body shape more rounded, also affecting muscle fibre orientation. The stacking of sarcomeres and myofibril arrangement show a less regular pattern. Finally, expression levels of several genes were changed. Together, these changes in expression indicate that muscle growth is not impeded and energy metabolism is not changed by the decrease in muscle activity but that the composition of muscle is altered. In addition, skin stiffness is affected. In conclusion, the lack of muscle fibre activity did not prevent the basal muscle components developing but influenced further organisation and differentiation of these components.

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Section: Muscle Fibre Morphologysupporting

confidence: 43%

mentioning

confidence: 98%

Effects of decreased muscle activity on developing axial musculature innicb107mutant zebrafish (Danio rerio)

Meulen

Schipper

Leeuwen

et al. 2005

Journal of Experimental Biology

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“…Embryonic myotomes have a simple block shape in two-dimensional projections, which transforms to a V-shape in a rostral to caudal progression. In zebrafish, the adult myotome shape is not attained until 6 weeks after hatching (Raamsdonk et al, 1974). In adult stages, the myotomes have a W-shape in two dimensions, but consist of a series of overlapping cones in three dimensions (Van Leeuwen, 1999).…”

Section: Myotomal Muscle In Teleost Fishmentioning

confidence: 99%

Environment and plasticity of myogenesis in teleost fish

Johnston

2006

Journal of Experimental Biology

317

276

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Embryonic development in teleosts is profoundly affected by environmental conditions, particularly temperature and dissolved oxygen concentrations. The environment determines the rate of myogenesis, the composition of sub-cellular organelles, patterns of gene expression, and the number and size distribution of muscle fibres. During the embryonic and larval stages, muscle plasticity to the environment is usually irreversible due to the rapid pace of ontogenetic change. In the early life stages, muscle can affect locomotory performance and behaviour, with potential consequences for larval survival. Postembryonic growth involves myogenic progenitor cells (MPCs) that originate in the embryo. The embryonic temperature regime can have long-term consequences for the growth of skeletal muscle in some species, including the duration and intensity of myotube formation in adult stages. In juvenile and adult fish, abiotic (temperature, day-length, water flow characteristics, hypoxia) and biotic factors (food availability, parasitic infection) have complex effects on the signalling pathways regulating the proliferation and differentiation of MPCs, protein synthesis and degradation, and patterns of gene expression. The phenotypic responses observed to the environment frequently vary during ontogeny and are integrated with endogenous physiological rhythms, particularly sexual maturation. Studies with model teleosts provide opportunities for investigating the underlying genetic mechanisms of muscle plasticity that can subsequently be applied to non-model species of more ecological or commercial interest.

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“…Located at the distal end of the common pathway and defining the nascent horizontal myoseptum, muscle pioneers are distinguishable from other somitic cells as the first to express muscle-specific characteristics (Waterman, 1969;van Raamsdonk et al, 1974;Myers et al, 1986;Felsenfeld et al, 1991;Hatta et al, 1991a) and assemble elements necessary for functional neuromuscular activity Hanneman and Westerfield, 1989;Westerfield, 1990, 1992). Zebrafish muscle pioneers fulfill criteria distinguishing guidepost cells in grasshoppers (for review, see Jellies, 1990;Palka et al, 1992) and intermediate targets in the rat CNS (Bovolenta and Dodd, 1990), mouse optic chiasm (Sretavan et al, 1995), and chick hindlimb plexus (Lance-Jones and Dias, 1991).…”

Section: Abstract: Acetylcholine Receptors; Neuromuscular Junctions;mentioning

confidence: 99%

Pathfinding by Identified Zebrafish Motoneurons in the Absence of Muscle Pioneers

et al. 1997

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To identify the cellular cues that guide zebrafish neuronal growth cones to their targets, we examined interactions between identified motor growth cones and identified muscle fibers and tested whether these fibers were required for growth cone navigation. Caudal primary motoneurons (CaPs) and middle primary motoneurons (MiPs) are identified motoneurons that innervate cell-specific regions of the myotome. Growth cones of both cells initially extend along a common pathway and then pause at a set of identified muscle fibers, called muscle pioneers, before diverging along cell-specific pathways. Muscle pioneers are intermediate targets of both CaP and MiP Liu and Westerfield, 1990); both motoneurons extend their growth cones directly to the muscle pioneers on which the first functional neuromuscular contacts form, suggesting that muscle pioneers may provide guidance information to these growth cones. We tested this idea by ablating muscle pioneers and observing the resulting motor axonal trajectories. Both CaP and MiP ultimately formed normal axonal arbors after muscle pioneer ablation, showing that muscle pioneers are unnecessary for formation of correct axonal trajectories; however, although final cellular morphology was correct in the absence of muscle pioneers, MiP growth cones branched abnormally or extended ventrally beyond the common pathway. Ablation of CaP and the muscle pioneers together increased the aberrant behavior of the MiP growth cone. Our results provide evidence that an intermediate target, the muscle pioneers, affects motor axonal extension without altering target choice, suggesting that other cues also contribute to proper pathway navigation. Key words: acetylcholine receptors; neuromuscular junctions; axogenesis; zebrafish motoneurons; muscle pioneers; pathway navigationThe environment through which growth cones navigate contains cues that regulate neuronal pathfinding (Frank and Wenner, 1993;Goodman and Shatz, 1993;Keynes and Cook, 1995). En route to their synaptic targets, neurons may project axons to intermediate targets that influence subsequent pathway choice . For example, some grasshopper pioneer neurons project to guidepost cells (Bentley and Keshishian, 1982) that are required for normal pathfinding (Bentley and Caudy, 1983). Chick hindlimb motoneurons (Lance-Jones and Landmesser, 1981; Tosney and Landmesser, 1985a,b;Landmesser, 1992) and spinal commissural neurons (Bovolenta and Dodd, 1991) also project to specific intermediate targets, which appear to influence extension. These results suggest that intermediate targets serve as choice points for pathway selection.We examined the role of potential intermediate targets in the pathway choices of zebrafish primary motoneurons. We focused on the first two primary motoneurons to extend growth cones out of the spinal cord: C aP and MiP (see Fig. 1) Myers et al., 1986). The C aP growth cone pioneers a common pathway to the nascent horizontal myoseptum, where it pauses before selecting its cell-specific pathway along ventral myotome Myers e...

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Differentiation of the musculature of the teleost Brachydanio rerio

Cited by 53 publications

References 20 publications

Effects of decreased muscle activity on developing axial musculature innicb107mutant zebrafish (Danio rerio)

Effects of decreased muscle activity on developing axial musculature innicb107mutant zebrafish (Danio rerio)

Environment and plasticity of myogenesis in teleost fish

Pathfinding by Identified Zebrafish Motoneurons in the Absence of Muscle Pioneers

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