Difficulties in emotion regulation and impulse control during cocaine abstinence

Fox, Helen; Axelrod, Seth R.; Paliwal, Prashni; Sleeper, Jim; Sinha, Rajita

doi:10.1016/j.drugalcdep.2006.12.026

Cited by 305 publications

(251 citation statements)

References 19 publications

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“…Total DERS scores in PCD (n ¼ 14, one PCD did not complete the assessment) ranged from 36 to 134 (median ¼ 96.5) and between 6 and 25 (median ¼ 11.5) in the impulse control subscale, consistent with our previous report in a larger sample of PCD (average total DERS score ¼ 86, compared to average total DERS score ¼ 61 of control subjects, Fox et al, 2007). Linear regression analyses indicated that rACC activity correlated inversely with the DERS total score (r ¼ À0.541; p ¼ 0.046; Figure 3a) and the impulse control subscale score (r ¼ À0.713; p ¼ 0.004; Figure 3b).…”

Section: Neural Correlates Of Impulse Control Difficulties In Cocainesupporting

confidence: 88%

“…The DERS is a 36-item self-report measure, with each item rated on a 5-point analog scale: 1 ¼ almost never; 2 ¼ sometimes; 3 ¼ about half of the time; 4 ¼ most of the time; 5 ¼ almost always. It has been shown to have high internal consistency, test-retest reliability, and construct validity in the general population and in cocaine-dependent patients (Fox et al, 2007;Gratz and Roemer, 2004 The total score of DERS ranges from 36 to 180 and the impulse control subscale score ranges from 6 to 30, with higher score indicating greater emotion dysregulation and difficulties in impulse control. Abstinent cocaine patients were found to have persistent problems in impulse control compared to healthy individuals (Fox et al, 2007).…”

Section: Subjects Informed Consent and Assessment Of Impulse Controlmentioning

confidence: 99%

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Neural Correlates of Impulse Control During Stop Signal Inhibition in Cocaine-Dependent Men

Huang

Yan

et al. 2007

Neuropsychopharmacol

164

126

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Altered impulse control is associated with substance use disorders, including cocaine dependence. We sought to identify the neural correlates of impulse control in abstinent male patients with cocaine dependence (PCD). Functional magnetic resonance imaging (fMRI) was conducted during a stop signal task that allowed trial-by-trial evaluation of response inhibition. Fifteen male PCD and 15 healthy control (HC) subjects, matched in age and years of education, were compared. Stop signal reaction time (SSRT) was derived on the basis of a horse race model. By comparing PCD and HC co-varied for stop success rate, task-related frustration rating, and post-error slowing, we isolated the neural substrates of response inhibition, independent of attentional monitoring (of the stop signal) and post-response processes including affective responses and error monitoring. Using region of interest analysis, we found no differences between HC and PCD who were matched in stop signal performance in the pre-supplementary motor area (pre-SMA) previously shown to be associated with SSRT. However, compared with HC, PCD demonstrated less activation of the rostral anterior cingulate cortex (rACC), an area thought to be involved in the control of stop signal inhibition. The magnitude of rACC activation also correlated negatively with the total score and the impulse control subscore of the Difficulty in Emotion Regulation Scale in PCD. The current study thus identified the neural correlates of altered impulse control in PCD independent of other cognitive processes that may influence stop signal performance. Relative hypoactivation of the rACC during response inhibition may represent a useful neural marker of difficulties in impulse control in abstinent cocaine-dependent men who are at risk of relapse.

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Section: Neural Correlates Of Impulse Control Difficulties In Cocainesupporting

confidence: 88%

Section: Subjects Informed Consent and Assessment Of Impulse Controlmentioning

confidence: 99%

Neural Correlates of Impulse Control During Stop Signal Inhibition in Cocaine-Dependent Men

Huang

Yan

et al. 2007

Neuropsychopharmacol

164

126

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“…In another study, those who were withdrawing from cocaine, scored high on lack of emotional clarity, lack of emotional awareness, and limited access to emotion regulation strategies (Fox, Axelrod, Paliwal, Sleeper, & Sinha, 2007). Consistent with the previous study on alcohol-dependent people, lack of emotional clarity and lack of emotional awareness were more impaired than other components, which is in accordance with present study (Fox, Hong, & Sinha, 2008).…”

Section: Discussionsupporting

confidence: 90%

Emotion Regulation Problems and Addiction Potential in Iranian Students

Rahbarian

mohammadi

Abasi

et al. 2017

PCP

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Objective: Recent studies have shown that emotion dysregulation is one of the most significant factors in young people's tendency towards risky behaviors. Therefore, it seems necessary to study the role of emotion regulation strategies in drug-related behaviors. The goal of the present study was to examine the relationship between emotion regulation strategies, and addiction potential in the Iranian student population. Methods:In this cross sectional study, a convenient sampling method was used to select a total of 388 students from the universities in Tehran. The Difficulties in Emotion Regulation Scale (DERS) and Addiction Potential Scale (IAPS) were used to collect data. The study data were analyzed using the Pearson's correlation coefficient and hierarchical regression analysis.Results: According to the study results, limited access to emotion regulation strategies was the sole predictor of active addiction potential (t=2.79, P<0.01). Passive addiction potential was predicted by emotional awareness (t=4.89, P<0.001) and also by limited access to emotion regulation strategies (t=5.01, P<0.01). Conclusion:Emotion regulation strategies and emotional awareness in relation to other components of emotion regulation were found to have more association with addiction potential. It was also seen that emotion regulation strategies training was effective in the prevention of drug dependence.

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“…Previous studies have confirmed that greater motor and cognitive impulsivity is an imperative risk that reason for substance abuse Mitchell 2005. Stressful situations directly related to lack of impulse control that may direct towards an inappropriate expression of an impulsive behavior [33].…”

Section: Resultsmentioning

confidence: 99%

Efficacy of Acceptance and Mindful Based Relapse Prevention Program on Emotion Regulation Difficulty among Alcoholics in Kerala India

George¹

2015

J Alcohol Drug Depend

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Alcoholism is the devastating deadly disease destructively affects the individual, family and society. It is progressive and damaging that controls thinking and emotions of the alcoholic and produces severe consequences on physical and psychological well-being. Dysregulation of emotions is the important causal factor of alcohol dependence and relapse vulnerability. Growing evidence suggests that emotion regulation underlie clinically significant behaviors and psychological difficulties among the alcoholics. In response to these problems researcher integrates a focuses on difficulties in emotion regulation developed an intervention program based on acceptance and commitment strategy along with mindfulness and behavior change process. The study has two phases; Program development and assessment of the efficacy of the program in reducing emotion regulation difficulty thereby total abstinence and replacement of addictive pattern of behavior through experimental methods. Total 32 alcohol dependence randomly assigned to control (N=16) and experimental (N=16) situation. The difficulties in emotion regulation (DERS) scale was administered. The mean, paired sample t-test, independent sample t-test, and Cohen's d were utilized for data analysis. The null hypothesis tested at 0.05 level of significant. Pre-test and post-test scores of the experimental group showed significant difference (P=0.00) that revealed the effectiveness of the intervention program.

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Difficulties in emotion regulation and impulse control during cocaine abstinence

Cited by 305 publications

References 19 publications

Neural Correlates of Impulse Control During Stop Signal Inhibition in Cocaine-Dependent Men

Neural Correlates of Impulse Control During Stop Signal Inhibition in Cocaine-Dependent Men

Emotion Regulation Problems and Addiction Potential in Iranian Students

Efficacy of Acceptance and Mindful Based Relapse Prevention Program on Emotion Regulation Difficulty among Alcoholics in Kerala India

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