Difficulties in the diagnosis of stroke in pregnant women

Елисеев, Е. В.; Дорошенко, Д.А.; Ov, Averkov; Konysheva, O.V.; Камчатнов, П Р; Zubarev, A. R.

doi:10.17116/jnevro20171173220-25

Z. nevrol. psikhiatr. im. S.S. Korsakova

2017

DOI: 10.17116/jnevro20171173220-25

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Difficulties in the diagnosis of stroke in pregnant women

Е. В. Елисеев

Д.А. Дорошенко

Averkov Ov

et al.

Abstract: A timely differential diagnosis of pathological conditions with different symptoms of stroke at the different stages of medical care of pregnant women helps to choose an optimal treatment plan and improve the outcome.

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The role of arterial hypertension in the development of cerebrovascular diseases in pregnancy

Чухловина

Medvedev

2018

Arter. gipertenz.

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Nowadays, the risk factors, improvement of diagnosis and treatment of cardiovascular diseases are of particular interest. Arterial hypertension (HTN) is known to contribute to cardiovascular disease and to be a risk factor for cerebrovascular diseases. HTN during pregnancy and in the postpartum period draws particular attention. Throughout the world, hypertension during pregnancy remains the leading cause of maternal and child morbidity and mortality. To our knowledge, only a few works studied neurological disorders associated with HTN in pregnant women. In this connection, the purpose of our review was to analyze the role of HTN in the development of cerebrovascular diseases in pregnancy. Pregnant women with HTN show 5,2-fold higher frequency of strokes than normotensive women. The risk of stroke increases from the third trimester of pregnancy to six weeks of the postpartum period. The pregnant women with HTN develop changes in the coagulation system leading to the formation of arterial and venous thromboses in the cerebrovascular circulation. The presence of preeclampsia (PE) is associated with the 7–9-fold increase in the risk of stroke. Endothelial dysfunction is one of the leading links in the pathogenesis of PE. The PE is associated with an increase in anti-angiogenic factors and a decrease in angiogenic factors. Thus, the measures preventing the development of cerebrovascular diseases in pregnant women with HTN, include identification of prehypertension in women of childbearing age, the improvement of HTB management strategies, and an interdisciplinary approach to the diagnostic and treatment process involving the obstetrician, the therapist, the cardiologist and the neurologist.

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The role of arterial hypertension in the development of cerebrovascular diseases in pregnancy

Чухловина

Medvedev

2018

Arter. gipertenz.

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show abstract

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Difficulties in the diagnosis of stroke in pregnant women

Abstract: A timely differential diagnosis of pathological conditions with different symptoms of stroke at the different stages of medical care of pregnant women helps to choose an optimal treatment plan and improve the outcome.

Cited by 1 publication

References 20 publications

The role of arterial hypertension in the development of cerebrovascular diseases in pregnancy

The role of arterial hypertension in the development of cerebrovascular diseases in pregnancy

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