Difficulties in the fine needle aspiration (FNA) diagnosis of schwannoma

Yu, Gordon H.; Sack, Martha J.; Baloch, Zubair; Gupta, Prabodh K.

doi:10.1046/j.1365-2303.1999.00132.x

Cited by 82 publications

(64 citation statements)

References 11 publications

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“…However, schwannomas are frequently difficult to characterize on FNAC. FNAC of schwannoma often results in hypocellular, nondiagnostic specimens, due to the presence of either significant cystic degeneration or a dense stromal component [12]. This was true in the present series; however, we could confirm by FNA that the tumors were avascular.…”

Section: Discussioncontrasting

confidence: 63%

Diagnosis and management of cervical sympathetic chain schwannoma: A review of 9 cases

Tomita¹,

Ozawa²,

Sakamoto³

et al. 2009

Acta Oto-Laryngologica

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MRI revealed 3 of 9 cases (33%) splayed the carotid bifurcation and displayed marked contrast enhancement with gadolinium. All patients underwent surgical excision of the mass with minimal blood loss. Postoperative Horner's syndrome was encountered in all patients, which required no treatment. Marked gadolinium enhancement tended to be associated with histological findings such as intratumoral hemorrhage and vasodilation.

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Section: Discussioncontrasting

confidence: 63%

Diagnosis and management of cervical sympathetic chain schwannoma: A review of 9 cases

Tomita¹,

Ozawa²,

Sakamoto³

et al. 2009

Acta Oto-Laryngologica

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“…One of the main reasons that neurilemoma may be difficult to diagnose from cytological smears is the high frequency of poor cellularity or lack of cells, particularly from cystic degenerated lesions [5,[10][11]. In our study of 116 cases, 27 aspirates were insufficient for diagnosis and an additional 24 were cell poor but considered evaluable.…”

Section: Discussionmentioning

confidence: 69%

“…The diagnosis may be difficult to render from FNA smears, as neurilemomas share some features with other spindle cell lesions [1][2][3][4][5][6][7][8].…”

Section: Introductionmentioning

confidence: 99%

Fine-needle aspiration of neurilemoma (schwannoma). A clinicocytopathologic study of 116 patients

et al. 2006

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The preoperative fine-needle aspiration cytology (FNAC) diagnoses in 116 surgically excised neurilemomas were reviewed and compared with the corresponding histopathologic diagnoses made on surgical specimens and with clinical data. In addition, the utility of adjunctive techniques was analyzed and other spindle-cell lesions in the differential diagnoses were discussed. An unequivocal, benign diagnosis was rendered by FNAC in 80 cases, 67 of which were correctly labelled as neurilemoma in a review of the original cytology reports. There were six false positive malignant diagnoses while 23 smears were considered insufficient and seven inconclusive as to whether benign or malignant. On reevaluation, the diagnostic smears in most cases contained spindle cells with wavy nuclei embedded in a fibrillar, occasionally collagenous and/or myxoid matrix and Antoni A /Antoni B tissue fragments. A moderate to abundant admixture of round to oval cells was also frequent. Nuclear palisading was seen in 41 smears with distinctive Verocay bodies in 10. Markedly pleomorphic nuclei were seen in smears from eight ancient and six conventional neurilemomas, and slight to moderate nuclear pleomorphism was observed in 38 additional cases. Thus most neurilemomas have distinct cytomorphologic features that allow correct diagnosis. The major problem in FNAC of neurilemoma is to obtain sufficient material. Furthermore aspirates showing predominantly Antoni A features, nuclear pleomorphism and/or myxoid changes can easily be confused with other types of benign or malignant soft tissue tumors.

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“…This situation is analogous to that found in benign nerve sheath tumors. 5 Radiographie evaluation is complementary to clinical findings. Due to the superior soft tissue resolution of MRI over computed tomography, as well as its multiplanar capabilities, MRI is the imaging modality of choice for evaluating these lesions.…”

Section: Discussionmentioning

confidence: 99%

Nuchal Fibroma: A Clinicopathological Review

Samadi

McLaughlin

Loevner

et al. 2000

Ann Otol Rhinol Laryngol

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Nuchal fibroma, or collagenosis nuchae, is a benign soft tissue tumor that arises from the posterior cervical subcutaneous tissue, with a predilection for the interscapular and paraspinal regions. Because of its benign clinical course and its close histopathologic similarity to other benign head and neck lesions, this lesion may be misdiagnosed and underreported. The purpose of this paper is to review the histopathologic and radiologic findings unique to nuchal fibroma, and compare and contrast it to the other soft tissue neoplasms within the clinical differential diagnosis. These include several benign (elastofibroma, lipoma, fibrolipoma, nodular fasciitis) and rare malignant entities (fibrosarcoma, liposarcoma, fibromatosis).

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Difficulties in the fine needle aspiration (FNA) diagnosis of schwannoma

Cited by 82 publications

References 11 publications

Diagnosis and management of cervical sympathetic chain schwannoma: A review of 9 cases

Diagnosis and management of cervical sympathetic chain schwannoma: A review of 9 cases

Fine-needle aspiration of neurilemoma (schwannoma). A clinicocytopathologic study of 116 patients

Nuchal Fibroma: A Clinicopathological Review

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