Diffuse Alveolar Hemorrhage Following Bleach Ingestion and Intravenous Injection

Dennis, Christopher J.; Trueblood, Eric; Frenia, Douglas

doi:10.1378/chest.134.4_meetingabstracts.c40001

Cited by 3 publications

(4 citation statements)

References 2 publications

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“…Dennis et al in 2008 reported a case of diffuse alveolar hemorrhage following the ingestion and IV injection of bleach. 19 Our reported patient suffered from no serious complications after the IV injection of a small amount of sodium hypochlorite, which is consistent with the other reported case of a relatively small amount of bleach. Also this case highlights a rare cause of VT.…”

Section: Discussionsupporting

confidence: 92%

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Venous thrombosis following intravenous injection of household bleach

et al. 2012

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Sodium hypochlorite (NaClO) is used extensively as a disinfectant or bleaching agent. Most studies describe ingestion or inhalation route of this product with rare complication and fatalities. Despite global daily exposures, data about bleach injection is limited. Here we report intentional infusion of 20 mL, sodium hypochlorite 5% diluted in 500 mL normal saline 1.5 h prior admission. Clinical manifestation included local pain and edema. There were no laboratory abnormalities in the patient. Doppler sonography revealed thrombosis in superficial (antecubital and basilic) veins. Limb elevation, warm compress, and ibuprofen relived pain and edema after 3 days.

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Section: Discussionsupporting

confidence: 92%

“…Dennis et al in 2008 reported a case of diffuse alveolar hemorrhage following the ingestion and IV injection of bleach. 19…”

Section: Discussionmentioning

confidence: 99%

Venous thrombosis following intravenous injection of household bleach

et al. 2012

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“…Her oxygenation improved significantly in the next three days, and she was discharged on a steroid taper with a complete resolution of symptoms. In this case, it was hypothesized that injury resulted from direct damage to alveolar capillaries by sodium hypochlorite delivered intravenously [ 14 ].…”

Section: Methodsmentioning

confidence: 99%

“…Intravenous exposures typically occur accidentally in intravenous drug users or intentionally as self-harm attempts. A case of DAH following the ingestion and intravenous injection 12 ml of sodium hypochlorite in her arms and legs during a suicide attempt was reported in a 42-year-old woman [ 14 ]. A 30-year-old man was intentionally infused with 20 mL of 5% sodium hypochlorite in 500 mL normal saline.…”

Section: Methodsmentioning

confidence: 99%

Health effects of sodium hypochlorite: review of published case reports

Chung

Ryu

Yoon

et al. 2022

Environ Anal Health Toxicol

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Sodium hypochlorite is widely used as the main component of cleaners and has an excellent bleaching and sterilizing effect in living and medical environments. In addition to bleaching, it is used for wastewater treatment and for sterilization in food factories, and also for disinfectants during the COVID-19 pandemic. This study analyzed reports of the health effects of sodium hypochlorite and classified them by toxicity along the exposure pathway. Most case reports described the health effects of acute high-concentration exposure, with a common case being dental exposure, mainly during treatment.

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Diagnosis and treatment of sodium hypochlorite poisoning with ingestion of household bleaching agents

Moon¹,

Chun²,

Cho³

2023

J Korean Med Assoc

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Background: Sodium hypochlorite is commonly used as a household bleaching agent (for example, the Clorox brand). Sodium hypochlorite poisoning with ingestion of a bleaching agent is often observed in clinical practice.Current Concepts: Ingestion (intentional or accidental) is the most common route of exposure to household bleaching agents. Accidental ingestion of household bleaching agents is rarely clinically important. However, ingestion of a large amount of a dilute formulation or a high-concentration preparation of bleaching agents can result in severe and rarely fatal corrosive injury. Therefore, prompt supportive care is essential because a specific antidote is currently unavailable. Severe poisoning requires hospital admission. Emergency endoscopy and thoracic and abdominal computed tomography are warranted to aid with diagnosis and management of hypochlorite-induced corrosive injury in patients with severe poisoning, who develop clinical features suggestive of corrosive injury.Discussion and Conclusion: Intentional poisoning, which accounts for most cases of household bleaching agent poisonings in Korea, is likely to cause severe corrosive injuries. Therefore, it is necessary to gain deeper and accurate understanding of the clinical aspects and treatment of poisoning by household bleaching agents.

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Diffuse Alveolar Hemorrhage Following Bleach Ingestion and Intravenous Injection

Cited by 3 publications

References 2 publications

Venous thrombosis following intravenous injection of household bleach

Venous thrombosis following intravenous injection of household bleach

Health effects of sodium hypochlorite: review of published case reports

Diagnosis and treatment of sodium hypochlorite poisoning with ingestion of household bleaching agents

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