Diffuse alveolar hemorrhage from metastatic cardiac angiosarcoma of the lung successfully treated with paclitaxel chemotherapy: A case report and brief literature review

A Case of Metastatic Malignancy Presenting as Diffuse Alveolar Hemorrhage, a Diagnostic and Management Challenge!

“…The reason this case has been brought up and presented is the unusual course that this patient took and the unlikely diagnosis based on this patient's age and history. DAH's initial presenting symptom is considered to be hemoptysis 4,5,6 , but in our patient majorly hemoptysis became apparent during hospital stay, which is similar to the results shown by Rabe et all 7 where hemoptysis was not a prominent feature in majority of patients (97%). Their results also showed that patient with non-immune induced DAH had a significantly worse prognosis, and majority of classical DAH cases are immunologically mediated.…”

“…Their results also showed that patient with non-immune induced DAH had a significantly worse prognosis, and majority of classical DAH cases are immunologically mediated. These findings were also supported by the case reports by Yang et al 6 , where patients with the rare cardiac angiosarcoma presented as DAH, with an extremely poor prognosis. Interestingly, another research revealed contrary findings in this regard that younger patients with immune DAH not only have severe presentation but also worse outcomes 8 .…”

Cardiac angiosarcoma with metastatic to lung, brain, and bone

“…Transbronchial biopsy is less complicated and invasive but previous studies have often reported failure to diagnose [ [24] , [25] ]. There are a few reports of successful transbronchial biopsy [26] . Though our patient was diagnosed by transbronchial biopsy, 5 of 6 specimens did not lead to a diagnosis.…”