Diffuse and Banded Melanin Pigmentation in Nails

Leyden, James J.; Spott, David A.; Goldschmidt, Herbert

doi:10.1001/archderm.1972.01620070020007

Cited by 98 publications

(35 citation statements)

References 6 publications

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“…20 However, the most common cause of longitudinal melanonychia is benign racial pigmentation. 21 Mucosal and facial pigmentation without evidence of intestinal polyposis has been found in relatives of patients with PJS. 22 Several authors have also described patients with characteristic perioral and intraoral pigmented macules but no intestinal polyposis and no family history, postulating a "forme fruste" of PJS.…”

Section: Discussionmentioning

confidence: 99%

Laugier-Hunziker syndrome: an important differential diagnosis for Peutz-Jeghers syndrome

Lampe¹,

Hampton²,

Woodford-Richens³

et al. 2003

Journal of Medical Genetics

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Section: Discussionmentioning

confidence: 99%

Laugier-Hunziker syndrome: an important differential diagnosis for Peutz-Jeghers syndrome

Lampe¹,

Hampton²,

Woodford-Richens³

et al. 2003

Journal of Medical Genetics

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“…Nail pigmentation in the form of pigmented bands is seen 25% of American blacks at the age of 10, and the prevalence rises to 96% by the age of 50 years (4). In Indian or Mongolian races, the prevalence of nail pigmentation is not precisely known, but it is probably high (5).…”

Section: Discussionmentioning

confidence: 99%

Laugier‐Hunziker Syndrome

Kanwar

Kaur

et al. 2001

The Journal of Dermatology

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“…In another study, 73% of the patients with skin phototypes IV, V, and VI had LM on physical examination [16]. It is frequently seen in the African-American population, with an estimated 100% of the black patients over 50 years of age having melanonychia [17]. In a report on Chinese patients with LM, there was an increasing prevalence with age, peaking at 1.7% in subjects older than 30 [18].…”

Section: Discussionmentioning

confidence: 99%

Assessment of Patient Knowledge of Longitudinal Melanonychia: A Survey Study of Patients in Outpatient Clinics

Halteh¹,

Scher²,

Artis³

et al. 2016

Skin Appendage Disord

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Importance: Subungual melanoma (SM) is a rare subtype of cutaneous melanoma but carries a worse prognosis than similarly staged cutaneous melanomas. Assessing patient knowledge of melanonychia is integral to early diagnosis of SM. Objectives: The aim of this paper is to determine patient knowledge of longitudinal melanonychia (LM) and warning signs for SM, frequency of nail self-examinations, and satisfaction of patients with their physician's nail examinations. Design, Setting, and Participants: We conducted a survey-based study of 363 random patients at Weill Cornell Medicine in New York, USA, performed at 3 different clinics: a general dermatology clinic (n = 167), a nail specialty clinic (n = 44), and a primary care clinic (n = 152). Main Outcomes and Measures: Knowledge of the ABCDEF mnemonic for SM was compared to the ABCD mnemonic for cutaneous melanoma. Analyses were performed for patient behavior regarding suspicious nail changes as well as satisfaction with nail counseling and examination. Results: Only 5% (18/363) of the patients in our study had heard of the ABCDEF mnemonic. In contrast, 9.9% (36/363) of the patients had heard of the ABCD mnemonic for cutaneous melanoma. In total, 37/363 (10.2%) patients reported having LM, 32.4% (12/37) of the patients noted changes in color or width of the band, and 10.8% (4/37) presented with pain or bleeding of the nail, with only 45.9% (17/37) seeking medical attention. Only 11.8% (43/363) of the patients stated that their physician asked them about nail changes, and 1.4% (5/363) of the patients stated that they were counseled about the ABCDEF mnemonic. In comparison, 13.8% (50/363) of the patients were advised on the ABCD mnemonic for the cutaneous melanoma mnemonic. While 70.2% (255/363) of the patients stated that they used sunscreen or wore sun-protective clothing, only 31.4% (114/363) assessed their nails for color changes, with 54.9% (128/233) of the patients categorizing themselves as “very unsatisfied” with the evaluation of their nails by their dermatologist. Conclusions and Relevance: Our data shows that there is a lack of patient knowledge of LM and warning signs for SM. Further testing is needed to determine whether educating patients about LM, warning signs for SM, and nail self-examinations would improve patient outcomes.

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Diffuse and Banded Melanin Pigmentation in Nails

Cited by 98 publications

References 6 publications

Laugier-Hunziker syndrome: an important differential diagnosis for Peutz-Jeghers syndrome

Laugier-Hunziker syndrome: an important differential diagnosis for Peutz-Jeghers syndrome

Laugier‐Hunziker Syndrome

Assessment of Patient Knowledge of Longitudinal Melanonychia: A Survey Study of Patients in Outpatient Clinics

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