Diffuse and marked breast uptake of both123I-BMIPP and99mTc-TF by myocardial scintigraphy

Abstract

Unexpected breast uptake was observed in a 32-year-old woman referred for evaluation of hypertrophic cardiomyopathy. Diffuse and marked bilateral breast uptake of 123I-BMIPP and 99mTc-TF was shown by both planar and SPECT imaging during the first study, and the uptake of both radionuclides had decreased significantly eleven months later. At the time of the first radionuclide examination, she was occasionally breast feeding her 2-year-old child and had small amounts of milk production. At the follow up examination, the frequency of breast feeding was significantly reduced and she produced only small amounts of milk. Therefore, the uptake of 123I-BMIPP and 99mTc-TF may have been caused by lactation.

Letter to the Editor Bilateral radioiodine uptake by the non-lactating breast of a single nulliparous woman: a and literature review

“…Bilateral breast uptake of 99m Tc-MIBI during the menstrual cycle and in the postmenopausal course has been reported, with 58% and 72% of the cases in the first and fourth weeks of the menstrual cycle, respectively, and with 5% of postmenopausal women studied [11]. Our patient was in the fourth week of her menstrual cycle.…”

Unilateral Breast Uptake of 99mTc-MIBI in a Lactating Woman During Myocardial Perfusion Imaging

“…Focal breast uptake of 99m Tc-MIBI, 201 Tl-, and 99m Tc-tetrofosmin has been serendipitously reported in malignant breast masses 3,4 a finding that led to use of these tracers for scintimammography to improve diagnostic accuracy 5,6 . However, diffuse bilateral breast uptake of 99m Tc-MIBI has only been reported in anecdotal case reports of postpartum patients 7,8 . Stabin et al 9 have shown that only 0.03% of initial 99m Tc dose is excreted in the breast milk.…”

“…5,6 However, diffuse bilateral breast uptake of 99m Tc-MIBI has only been reported in anecdotal case reports of postpartum patients. 7,8 Stabin et al 9 have shown that only 0.03% of initial 99m Tc dose is excreted in the breast milk. Even in a hypothetical scenario of continued breast feeding, an infant would receive a dose of 0.52 rem/mCi.…”