2001
DOI: 10.1007/s002920100491
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Diffuse Hämangiomatose von Leber und Milz beim Erwachsenen

Abstract: Diffuse hemangiomatoses are extremely rare in adults. The etiology and natural history of the disease are not well understood. A case of diffuse hemangiomatosis of the liver and spleen associated with progressive liver failure, thrombocytopenia, and disturbance of blood coagulation (comparable to Kasabach-Merritt syndrome) is presented in a 62-year-old male. We describe the histopathological and immunohistochemical findings and illustrate the morphological aspects of differential diagnosis, distinguishing the … Show more

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Cited by 18 publications
(3 citation statements)
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“…12) Case 6 in Table 1 had multiple skull hemangiomas associated with subcutaneous hemangiomas and Case 8 had another intraosseous lesion. We found no consensus on the terminology in the literature to describe multiple hemangiomas that affect multiple organs, but the terms``diffuse hemangiomatosis'' 17) or``multiple hemangiomatosis'' 21) have been used. The coexistence of calvarial cavernous hemangioma, especially if multifocal, with hemangiomas in other organs is very rare.…”
Section: Discussionmentioning
confidence: 99%
“…12) Case 6 in Table 1 had multiple skull hemangiomas associated with subcutaneous hemangiomas and Case 8 had another intraosseous lesion. We found no consensus on the terminology in the literature to describe multiple hemangiomas that affect multiple organs, but the terms``diffuse hemangiomatosis'' 17) or``multiple hemangiomatosis'' 21) have been used. The coexistence of calvarial cavernous hemangioma, especially if multifocal, with hemangiomas in other organs is very rare.…”
Section: Discussionmentioning
confidence: 99%
“…It occurs in all age groups, although hepatic hemangiomatosis occurs predominantly in infants and may cause life threatening conditions (1). However, diffuse hepatic hemangiomatosis in adults is very rarely encountered and moreso when observed without any other organ involvement (2-4). Although several cases of long-term adult survival of diffuse neonatal hemangiomatosis have been reported (5, 6), the etiology and natural history of diffuse hepatic hemangiomatosis remains unclear.…”
Section: Discussionmentioning
confidence: 99%
“…The most prevalent complication of DHH is liver failure [16,22,36,37]. In reported cases, other complications such as Kasabach-Merritt syndrome, disseminated intravascular coagulation, and cardiac or various organic dysfunctions have also been noted, invariably leading to exitus [13,35].…”
Section: Rare Liver Transplants Indications 21 Hepatic Hemangiomatosismentioning
confidence: 99%