Diffuse Large B-cell Lymphoma Diagnosed by Intracardiac Echocardiography-guided Cardiac Tumor Biopsy

Kamiya, Kiwamu; Sakakibara, Mamoru; Yamada, Shiro; Tan, Michinao; Furihata, Takaaki; Kubota, Kanako; Tsutsui, Hiroyuki

doi:10.2169/internalmedicine.51.6752

Cited by 10 publications

(8 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…ICE is known to give compatible or superior imaging quality to TEE in guiding transcatheter endomyocardial biopsy without the need for general anesthesia. 21) Although several case reports and the present case showed the usefulness and safety of ICE in differential diagnosis of cardiac masses including malignant tumors, [22][23][24][25] the diagnostic accuracy and complication rate of ICE-guided percutaneous transcatheter biopsy for cardiac masses need to be investigated.…”

Section: Discussionmentioning

confidence: 79%

Successful Transcatheter Diagnosis and Medical Treatment of Right Atrial Involvement in IgG4-related Disease

et al. 2018

View full text Add to dashboard Cite

IgG4-related disease (IgG4-RD) is a fibro-inflammatory disorder characterized by lymphoplasmacytic infiltration of numerous IgG4-positive plasma cells, leading to fibrous thickening in the affected tissue. Typical cardiovascular manifestations of IgG4-RD are periaortitis, coronary arteritis, and pericarditis. Rare cases of myocardial involvement in IgG4-RD have been reported, but surgical resection or open biopsy was required for the diagnosis in those cases. Here, we report a case in which percutaneous transcatheter biopsy under the guidance of intracardiac echocardiography was useful for diagnosis of IgG4-RD manifested as an intracavitary right atrial mass, extending into the superior vena cava. Successful transcatheter diagnosis of myocardial involvement of IgG4-RD led to immediate favorable response to steroid therapy. Including the present case, previous IgG4-RD cases with myocardial involvement are reviewed to delineate its clinical characteristics.

show abstract

Section: Discussionmentioning

confidence: 79%

Successful Transcatheter Diagnosis and Medical Treatment of Right Atrial Involvement in IgG4-related Disease

et al. 2018

View full text Add to dashboard Cite

show abstract

“…In addition to a report of cardiac tumors that were diagnosed by a PTB in the right ventricle, primary cardiac lymphoma diagnosed by a PTB in the right atrium has been reported. [ 6 7 ] We described a case of primary cardiac angiosarcoma that was diagnosed by PTB in the right atrium.…”

Section: Discussionmentioning

confidence: 99%

Primary angiosarcoma in the right atrium diagnosed by a cardiac tumor biopsy using intracardiac echocardiography

Naruse¹,

Kawasaki²,

Yanase³

et al. 2020

J Med Ultrasound

View full text Add to dashboard Cite

A 47-year-old woman consulted a doctor due to a persistent cough. Computed tomography revealed a 30 mm × 60 mm intracardiac mass in the right atrium. Because of lung metastasis, her respiratory status did not allow a more invasive procedure, such as general anesthesia. Although intracardiac echocardiography (ICE) during percutaneous transcatheter biopsy (PTB) is not covered by medical insurance, we performed PTB under ICE guidance. Pathology and immunohistochemistry revealed primary cardiac angiosarcoma. Primary cardiac angiosarcoma is a rare tumor with a poor prognosis. After seven cycles of chemotherapy, the pulmonary metastasis was clearly improved. The patient is alive 18 months after the first consult, even though the mortality of angiosarcoma is high. ICE during PTB allowed us to choose appropriate chemotherapy and improve her pulmonary metastasis. ICE during PTB reduces the need for a diagnostic open-chest procedure that requires a more invasive approach.

show abstract

“…Transvenous endomyocardial biopsy under TEE guidance is useful, simple, and safe [ 22 – 25 ] despite usually requiring local pharyngeal or general anesthesia. In contrast, the recently introduced procedure of transvenous biopsy via cardiac catheterization with the guidance of intracardiac echo-cardiography (ICE) does not require such anesthesia and can facilitate assessment of cardiac structure [ 26 – 30 ]. Physicians who are involved in diagnosing cardiac tumors should be well versed in use of ICE.…”

Section: Discussionmentioning

confidence: 99%

Cardiac Recurrence of Diffuse Large B-cell Lymphoma More Than a Decade After Attaining Complete Remission

et al. 2018

View full text Add to dashboard Cite

Patient: Female, 79Final Diagnosis: Cardiac recurrence of DLBCLSymptoms: Cardiogenic shockMedication: —Clinical Procedure: Biopsy specimenSpecialty: Cardiology/HematologyObjective:Unusual clinical courseBackground:Although diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma in adults, isolated cardiac recurrence of DLBCL which can cause fatal heart failure via various mechanisms is extremely rare. Furthermore, the frequency of recurrence of DLBCL more than 5 years after attaining complete remission is as low as 3.6%. The rate of complete remission and partial remission of DLBCL that have recurred 5 or more years after attaining the initial remission are reported to be 61% and 29%, respectively.Case Report:A 79-year-old female with a history of DLBCL at the age of 63 years was transferred to our hospital because of cardiogenic shock. Although cardiac tamponade was suspected, her hemodynamics did not improve with pericardiocentesis. Thoracotomy showed an elastic to hard tumor occupying most of the right ventricular wall. Cytological examination of the pericardial effusion and histological examination of a biopsy of the tumor yielded a diagnosis of DLBCL; this information was available only post mortem. Immunostaining of a biopsy specimen suggested that her cardiac tumor was a recurrence of her lymphoma diagnosed 16 years previously. Bone marrow aspiration was not performed; no recurrences were detected in any other site. This patient thus appeared to have an isolated cardiac recurrence of DLBCL.Conclusions:When managing a patient with a cardiac tumor and a past history of DLBCL, albeit more than a decade previously, establishing a histological diagnosis as early as possible would facilitate possible successful treatment and a good prognosis.

show abstract

Diffuse Large B-cell Lymphoma Diagnosed by Intracardiac Echocardiography-guided Cardiac Tumor Biopsy

Cited by 10 publications

References 26 publications

Successful Transcatheter Diagnosis and Medical Treatment of Right Atrial Involvement in IgG4-related Disease

Successful Transcatheter Diagnosis and Medical Treatment of Right Atrial Involvement in IgG4-related Disease

Primary angiosarcoma in the right atrium diagnosed by a cardiac tumor biopsy using intracardiac echocardiography

Cardiac Recurrence of Diffuse Large B-cell Lymphoma More Than a Decade After Attaining Complete Remission

Contact Info

Product

Resources

About