Diffuse Large B-Cell Lymphoma Presenting as Multiple Lymphomatous Polyposis of the Gastrointestinal Tract

B Cell Lymphoma Unclassifiable with Features Intermediate Between Diffuse Large B Cell and Burkitt Lymphoma—Presented with Multiple Lymphomatous Polyposis of Gastrointestinal Tract

“…Subsequent studies showed that follicular lymphoma [4], MALT lymphoma [10], and DLBCL [9] may also be presented as MLP. A recent report described small lymphocytic lymphoma [11], as a rare form of MLP.…”

“…It is generally thought to be an expression of mantle cell lymphoma [8]. However, recent studies suggest that MLP is a heterogeneous group that includes mantle cell origin [8], diffuse large B cell phenotype [9], MALT [10], small lymphocytic [11], and follicular center cell subtypes [4]. To the best of author's knowledge, MLP with recently described subtype of B cell lymphoma (DLBCL/BL) has never been described in the literature.…”

Primary intestinal diffuse large B-cell lymphoma forming multiple lymphomatous polyposis

“…tity defined as multiple lymphomatous polyposis (MLP), which is characterized by multiple polypoid lesions affecting the same or different GIS segments, and it is a quite rarely encountered developmental pattern (1,4,(8)(9)(10)(11)(12)(13)(14)(15). First described by Cornes in 1961, this developmental pattern accounts for 1-2% of GIS lymphomas (1,4,8,(10)(11)(12).…”

“…First described by Cornes in 1961, this developmental pattern accounts for 1-2% of GIS lymphomas (1,4,8,(10)(11)(12). MLP is thought to represent mantle cell lymphoma of the GI tract (13,(16)(17)(18)(19). MLP cases associated with DLBCL are very rare and are also controversial (9).…”

Endosopic Autofluorescence Imaging is Useful for the Differential Diagnosis of Intestinal Lymphomas Resembling Lymphoid Hyperplasia

“…5 Similarly, an endoscopic diagnosis of intestinal lymphoma is sometimes vague because of the diverse findings, including mass lesions with constriction, ulceration and protrusion, or diminutive lesions presenting as multiple polyps, fine granular mucosa, multiple scars, or swollen folds. [6][7][8][9] These problems associated with the histologic and endoscopic diagnosis can thus cause delays in the detection and/or result in incorrect staging followed by inadequate treatment of the intestinal lymphomas.…”