“…Studies have focused on the occurrence, fate, behavior, distribution, and toxicity of pharmaceuticals in wastewater influent and effluent (Gros et al, 2007), sludge (Radjenović et al, 2009), surface water (Rivera-Jaimes et al, 2018), and sediment and soil (Diaz-Cruz et al, 2003;Koba et al, 2018). Pharmaceuticals are released into the environment either as parent compound and as active/inactive metabolites (Christensen, 1998).…”