Diffuse sclerosing variant of papillary thyroid carcinoma: ultrasonographic and clinicopathological features in children/adolescents and adults

Chang, Qing; Zhang, R.; Sun, Chao; Li, L.; Wang, Shan; Wang, Q.; Li, Z.; Niu, Lijuan

doi:10.1016/j.crad.2022.01.051

Cited by 6 publications

(2 citation statements)

References 27 publications

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“…The differential diagnosis of multinodular goitre in CYP includes diffusely infiltrating papillary thyroid cancer that presents with enlargement of a lobe or the entire thyroid, very frequently associated with microcalcifications on neck US ( Wang et al 2022 ). Multinodular thyroid enlargement in CYP, especially if associated with palpable cervical lymph nodes, in a CYP with normal thyroid function therefore requires investigation by neck US.…”

Section: Resultsmentioning

confidence: 99%

Paediatric differentiated thyroid carcinoma: a UK National Clinical Practice Consensus Guideline

Howard

Freeston

Harrison³

et al. 2022

Endocrine-Related Cancer

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This guideline is written as a reference document for clinicians presented with the challenge of managing paediatric patients with differentiated thyroid carcinoma up to the age of 19 years. Care of paediatric patients with differentiated thyroid carcinoma differs in key aspects from that of adults, and there have been several recent developments in the care pathways for this condition; this guideline has sought to identify and attend to these areas. It addresses the presentation, clinical assessment, diagnosis, management (both surgical and medical), genetic counselling, follow-up and prognosis of affected patients. The guideline development group formed of a multi-disciplinary panel of sub-speciality experts carried out a systematic primary literature review and Delphi consensus exercise. The guideline was developed in accordance with The Appraisal of Guidelines Research and Evaluation Instrument II criteria, with input from stakeholders including charities and patient groups. Based on scientific evidence and expert opinion, 58 recommendations have been collected to produce a clear, pragmatic set of management guidelines. It is intended as an evidence base for future optimal management and to improve the quality of clinical care of Paediatric patients with differentiated thyroid carcinoma.

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Section: Resultsmentioning

confidence: 99%

Paediatric differentiated thyroid carcinoma: a UK National Clinical Practice Consensus Guideline

Howard

Freeston

Harrison³

et al. 2022

Endocrine-Related Cancer

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“…As the thyroid can often harbor chronic lymphocytic thyroiditis (CLT), many studies have reported that thyroid cancer, especially PTC, is related with CLT [ 61 , 62 ]. Warthin-like variant and diffuse sclerosing variant are histologic subtypes of PTC that are accompanied by an abundance of lymphoplasma cells [ 63 , 64 ]. PTC with CLT has good prognosis with limited disease progression [ 65 , 66 ]; however, PTC with tumor infiltrating lymphocytes is reported to be found at higher cancer stage and have more frequent lymph node metastases [ 67 ].…”

Section: Cell Component and Function Of Tumor Microenvironment In Thy...mentioning

confidence: 99%

Cell Component and Function of Tumor Microenvironment in Thyroid Cancer

Shin

Koo

2022

IJMS

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Thyroid cancer is the most common cancer in the endocrine system. Most thyroid cancers have good prognosis, but some of them are resistant to treatment or show aggressive behavior. Like other tumors, thyroid cancers harbor tumor microenvironment (TME) composed of cancer associated fibroblasts (CAF) and immune cells. Autoimmune lymphocytic thyroiditis can occur in the thyroid, and it may be associated with cancer development. TME is involved in tumor progression through various mechanisms: (1) CAF is involved in tumor progression through cell proliferation and extracellular matrix (ECM) remodeling; and (2) immune cells are involved in tumor progression through cell proliferation, angiogenesis, epithelial mesenchymal transformation (EMT), and immune suppression. These events are activated by various cytokines, chemokines, and metabolites secreted from cells that comprise TME. This review is focused on how CAF and immune cells, two important cell components of thyroid cancer TME, are involved in tumor progression, and will explore their potential as therapeutic targets.

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Clinical Advantages and Limitations of Tumors Displaying Minimal and Extensive Vascular Invasion

Eloy,

Cameselle-Teijeiro,

Abdulkader-Nallib

et al. 2023

Thyroid FNA Cytology

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Diffuse sclerosing variant of papillary thyroid carcinoma: ultrasonographic and clinicopathological features in children/adolescents and adults

Cited by 6 publications

References 27 publications

Paediatric differentiated thyroid carcinoma: a UK National Clinical Practice Consensus Guideline

Paediatric differentiated thyroid carcinoma: a UK National Clinical Practice Consensus Guideline

Cell Component and Function of Tumor Microenvironment in Thyroid Cancer

Clinical Advantages and Limitations of Tumors Displaying Minimal and Extensive Vascular Invasion

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