Diffuse Thyroid Uptake in FDG PET/ CT Scan cCan Predict Subclinical Thyroid Disorders

Hasan, Mustafa R.; Kadam, Satar M.; Essa, Samar I.

doi:10.24996/ijs.2022.63.5.15

Cited by 3 publications

(3 citation statements)

References 10 publications

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“…The treatment planning term describes the whole technical process, from patient data acquisition to treatment verification. There are many techniques to deliver the radiation dose to the tumor [6,7]. Intensity-Modulated Radiation Therapy (IMRT) and Volumetric Modulated Arc Therapy (VMAT) are modern planning approaches that combine linear accelerators to safely deliver precision radiation to a tumor while limiting the exposure to surrounding normal tissue.…”

Section: Introductionmentioning

confidence: 99%

Study the Quality of IMRT and VMAT Treatment Planning Techniques (TPS) Using Indices of Achievement (IOA) Nasopharyngeal Cancer Plans

Khalaf,

Basim Khalaf Rejah

2024

IHJPAS

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Volumetric Modulated Arc Therapy (VMAT) and Intensity Modulated Radiation Therapy (IMRT) are comparable for nasopharyngeal cancerous radiation therapy. This research intends to analyze the high-quality plan using accomplishment, conformance, and homogeneity criteria. The study involved 40 patients with a postnasal cancerous tumor. The patients underwent computed tomography (CT) simulation to scan the anatomical details of the patients' heads. Then, their data was forwarded to the treatment planning system (TPS) workstation for IMRT and VMAT planning. The plans were evaluated using the IOA, HI, and CI indices. The nasopharynx coverage results consist of the GTV and PTV at 95%. The statistical study reveals that VMAT provides much more coverage than IMRT for 95% GTV and 95% PTV. The results reveal that VMAT has a substantially better-quality plan (IOA) than IMRT. IMRT provides a superior CI, but VMAT protects the cochlea and optic nerves more effectively. In addition, the IMRT is advantageous for the preservation of additional OARs. There is no statistical difference in protection for the mandible and parotid glands between the two procedures. The VMAT has superior coverage for the gross and planned target volumes and achievement indices. The conformity of IMRT in the tumor target area is better, while VMAT can better protect the cochlea and optic nerves.

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Section: Introductionmentioning

confidence: 99%

Study the Quality of IMRT and VMAT Treatment Planning Techniques (TPS) Using Indices of Achievement (IOA) Nasopharyngeal Cancer Plans

Khalaf,

Basim Khalaf Rejah

2024

IHJPAS

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“…In the present day, ( 18 F-FDG) PET/CT scan is frequently used for staging, restaging, recurrence identification, and tracking of therapeutic response in a variety of malignant diseases [1]. 18 F-FDG PET/CT identifies malignant lesions by combining metabolic and anatomical information.…”

Section: Introductionmentioning

confidence: 99%

Reevaluation Body Weight and Age with Standardized Uptake Value in the Liver Cancer for [18F] FDG PET/CT

Hade,

Kadam,

Essa

2023

East Eur. J. Phys.

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Standardized uptake values, often known as SUVs, are frequently utilized in the process of measuring 18F-fluorodeoxyglucose (FDG) uptake in malignancies . In this work, we investigated the relationships between a wide range of parameters and the standardized uptake values (SUV) found in the liver. Examinations with 18F-FDG PET/CT were performed on a total of 59 patients who were suffering from liver cancer. We determined the SUV in the liver of patients who had a normal BMI (between 18.5 and 24.9) and a high BMI (above 30) obese. After adjusting each SUV based on the results of the body mass index (BMI) and body surface area (BSA) calculations, which were determined for each patient based on their height and weight. Under a variety of different circumstances, SUVs were evaluated based on their means and standard deviations. Scatterplots were created to illustrate the various weight and SUV variances. In addition to that, the SUVs that are appropriate for each age group were determined. SUVmax in the liver was statistical significantly in obese BMI and higher BSA, p- value <0.001). Age appeared to be the most important predictor of SUVmax and was significantly associated with the liver SUVmax with mean value (58.93±13.57). Conclusions: Age is a factor that contributes to variations in the SUVs of the liver. These age-related disparities in SUV have been elucidated as a result of our findings, which may help clinicians in doing more accurate assessments of malignancies. However, the SUV overestimates the metabolic activity of each and every individual, and this overestimation is far more severe in people who are obese compared to people who have a body mass index that is normal (BMI).

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“…18 F-FDG is distinguished by its relatively short half-life (109.8 minutes) that emits gamma rays at 1020 keV. The energy is sufficiently high to exit with minimal interactions with other tissues in the body [5].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the Influence of Body Mass Index and Signal-to-Noise Ratio on the PET/CT Image Quality in Iraqi Patients with Liver Cancer

Hade,

Essa

2023

East Eur. J. Phys.

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Image quality has been estimated and predicted using the signal to noise ratio (SNR). The purpose of this study is to investigate the relationships between body mass index (BMI) and SNR measurements in PET imaging using patient studies with liver cancer. Three groups of 59 patients (24 males and 35 females) were divided according to BMI. After intravenous injection of 0.1 mCi of 18F-FDG per kilogram of body weight, PET emission scans were acquired for (1, 1.5, and 3) min/bed position according to the weight of patient. Because liver is an organ of homogenous metabolism, five region of interest (ROI) were made at the same location, five successive slices of the PET/CT scans to determine the mean uptake (signal) values and its standard deviation. We obtained the liver's Signal-to-Noise Ratio from the ratio of both. Weight, height, SNR, and Body Mass Index were determined using a spreadsheet, and graphs were created to show the relationship between these variables. The graphs demonstrated that SNR decreases when BMI increases and that, despite an increase in injection dose, SNR also decreases. This is because heavier individuals take higher doses and, according to reports, have lower SNR. These results show that, despite receiving larger FDG doses, heavier patients' images, as measured by SNR, are of lower quality than thinner patients' images.

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Diffuse Thyroid Uptake in FDG PET/ CT Scan cCan Predict Subclinical Thyroid Disorders

Cited by 3 publications

References 10 publications

Study the Quality of IMRT and VMAT Treatment Planning Techniques (TPS) Using Indices of Achievement (IOA) Nasopharyngeal Cancer Plans

Study the Quality of IMRT and VMAT Treatment Planning Techniques (TPS) Using Indices of Achievement (IOA) Nasopharyngeal Cancer Plans

Reevaluation Body Weight and Age with Standardized Uptake Value in the Liver Cancer for [18F] FDG PET/CT

Evaluation of the Influence of Body Mass Index and Signal-to-Noise Ratio on the PET/CT Image Quality in Iraqi Patients with Liver Cancer

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