2017
DOI: 10.1089/pho.2016.4162
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Diffuse Urticarial Reaction Associated with Titanium Dioxide Following Laser Tattoo Removal Treatments

Abstract: Ours is the first documented case of a diffuse urticarial reaction following laser tattoo removal treatments that shows a strong association to titanium dioxide within the tattoo pigment. Herein, we describe a novel surgical approach to treat recalcitrant generalized allergic reaction to tattoo pigment.

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Cited by 7 publications
(4 citation statements)
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“…Interestingly, our 2 patients experienced delayed hypersensitivity reactions manifesting urticarial hives that occurred near eyebrows and at a distant, untreated tattoo site, which is yet to be reported with removal of cosmetic tattoos of the eyebrow. This urticarial reaction may have resulted from an immunologic response to the ink particles, especially titanium dioxide 18 .…”
Section: Discussionmentioning
confidence: 99%
“…Interestingly, our 2 patients experienced delayed hypersensitivity reactions manifesting urticarial hives that occurred near eyebrows and at a distant, untreated tattoo site, which is yet to be reported with removal of cosmetic tattoos of the eyebrow. This urticarial reaction may have resulted from an immunologic response to the ink particles, especially titanium dioxide 18 .…”
Section: Discussionmentioning
confidence: 99%
“…An analysis of diathermy instruments showed that cutting loops from microsurgical needle electrodes are made of pure W, 36 whereas Ti may originate from metal Ti or Ti-containing alloys used in biocompatible prosthetic devices, 37 pacemaker implants, 38 ear piercings, 1 or from drainage of the ink particles from a nearby tattoo. 39 Notably, tattoo pigments are frequently found in the skin and/or lymph nodes, in which they might induce sarcoidal or foreign-body granulomas or pseudolymphomas. 2 According to the color and the composition of the inks that were used, one or several pigmented granules might be found in the tissue.…”
Section: Discussionmentioning
confidence: 99%
“…Patients also may consider laser tattoo removal; however, providers should be aware that there have been rare reports of systemic urticarial reactions from this procedure. 24,25 Obviously limited by location and size, excision also may be offered.…”
Section: Management Of Tattoo Hypersensitivity Reactionsmentioning
confidence: 99%