Diffusion mechanism and release profile of a multivitamin from TiO2 hollow particles

Tominaga, Yoko; Kadota, Kazunori; Kitayama, Akira; Shimosaka, Atsuko; Yoshida, Mikio; Shirakawa, Yoshiyuki

doi:10.1016/j.apt.2019.09.006

Advanced Powder Technology

2019

DOI: 10.1016/j.apt.2019.09.006

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Diffusion mechanism and release profile of a multivitamin from TiO2 hollow particles

Yoko Tominaga

Kazunori Kadota

Akira Kitayama

et al.

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2021

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Particle Preparation and Morphology Control with Mutual Diffusion Across Liquid-Liquid Interfaces

Kadota

Shirakawa

2021

KONA

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Advanced functional materials require sophisticated control of particle characteristics. The bottom-up process has been extensively used to produce functional materials for controlling the particle properties of composite particles. We propose crystallization at liquid-liquid interfaces as an advanced particle formation method. This review introduces crystallization at a liquid-liquid interface based on several case studies used in various applications. Conventional crystallization has been generally used to produce crystals and particles with homogeneous particle properties. Liquid-liquid interfacial crystallization makes it possible to create composite particles with hetero-phase structures and interfaces. Liquid-liquid interfacial crystallization with an inkjet technique can control the droplet size accurately, and the shape and particle size distribution are successfully controlled in inorganic-organic composite particles. In addition, we succeed in creating organic-organic composite particles using the interfacial crystallization by an ultrasonic spray nozzle. The coating efficiency of organic particles on the particles is enhanced using the ultrasonic spray nozzle in comparison with anti-solvent crystallization. In this study, the fabrication of inorganic-organic composite particles using a coaxial tube reactor on the liquid-liquid interfacial crystallization is proven successful. These findings suggest that liquid-liquid interfacial crystallization is a promising means of efficiently producing composite particles because of their applicability to infusion in various processes.

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Particle Preparation and Morphology Control with Mutual Diffusion Across Liquid-Liquid Interfaces

Kadota

Shirakawa

2021

KONA

Self Cite

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Diffusion mechanism and release profile of a multivitamin from TiO2 hollow particles

Cited by 1 publication

References 42 publications

Particle Preparation and Morphology Control with Mutual Diffusion Across Liquid-Liquid Interfaces

Particle Preparation and Morphology Control with Mutual Diffusion Across Liquid-Liquid Interfaces

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