The innovations of science often point to ideas and behaviors that must spread and take root in communities to have impact. Ideas, practices, and behaviors need to go from accepted truths on the part of a few scientists to commonplace beliefs and norms in the minds of the many. Moving from scientific discoveries to public good requires social influence. We introduce a structured influence process (SIP) framework to explain how social networks (i.e., the structure of social influence) and human social motives (i.e., the process of social influence wherein one person's attitudes and behaviors affect another's) are used collectively to enact social influence within a community. The SIP framework advances the science of scientific communication by positing social influence events that consider both the "who" and the "how" of social influence. This framework synthesizes core ideas from two bodies of research on social influence. The first is network research on social influence structures, which identifies who are the opinion leaders and who among their network of peers shapes their attitudes and behaviors. The second is research on social influence processes in psychology, which explores how human social motives such as the need for accuracy or the need for affiliation stimulate behavior change. We illustrate the practical implications of the SIP framework by applying it to the case of reducing neonatal mortality in India. T here is compelling evidence that both in the developing and developed world the day a baby is born is the most dangerous of the child's life. In 2012, 2.9 million children died in their first month of life and over a third on their first day. India alone accounts for more than a quarter of the world's neonatal deaths, with 31 of every 1,000 children dying before age 28 d. Although the neonatal mortality rate (NMR) in India has been declining, it is still 10 times higher than in the developed world.From Scientific Discovery to Public Good Scientific discoveries stand to drastically reduce NMR, greatly improving the lives of the next generation of children living in the world's largest democracy. Although there is a substantial portfolio of actionable insights, often bolstered by multiple randomized control trials (RCTs), a pressing challenge confronting funders, health-care administrators, and workers is to scale up these practices from pilot projects to widespread practices. Ideas, facts, practices, and behaviors need to go from accepted truths on the part of a few scientists to commonplace beliefs and norms in the minds of the many health-care workers as well as the populace at large in places most in need of them. For instance, it is well documented that over a third of all neonatal deaths are caused by infection, and umbilical cord infection is a major risk factor for many of these (1). It is also well established in RCTs that applying an inexpensive topical solution of 4% chlorhexidine (CHG) to cleanse the cord reduced neonatal mortality in developing countries such as Nepal by 24%, with com...