Diffusion-weighted imaging for the detection of mesenteric small bowel tumours with Magnetic Resonance--enterography

Amzallag-Bellenger, Élisa; Soyer, Philippe; Barbe, Coralie; Nguyen, Truong Luong Francis; Amara, Nedjoua; Hoeffel, Christine

doi:10.1007/s00330-014-3303-x

Cited by 20 publications

(12 citation statements)

References 33 publications

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“…It has also been found to be useful in detection and characterization of extraintestinal manifestations and complications[ 57 ]. Use of DWI with MR enterography improves mesenteric and small bowel tumor detection compared to unenhanced MR-enterography[ 58 ].…”

Section: Clinical Applications Of Dwimentioning

confidence: 99%

Diffusion weighted imaging: Technique and applications

Baliyan¹,

Das²,

Sharma³

et al. 2016

WJR

294

185

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Diffusion weighted imaging (DWI) is a method of signal contrast generation based on the differences in Brownian motion. DWI is a method to evaluate the molecular function and micro-architecture of the human body. DWI signal contrast can be quantified by apparent diffusion coefficient maps and it acts as a tool for treatment response evaluation and assessment of disease progression. Ability to detect and quantify the anisotropy of diffusion leads to a new paradigm called diffusion tensor imaging (DTI). DTI is a tool for assessment of the organs with highly organised fibre structure. DWI forms an integral part of modern state-of-art magnetic resonance imaging and is indispensable in neuroimaging and oncology. DWI is a field that has been undergoing rapid technical evolution and its applications are increasing every day. This review article provides insights in to the evolution of DWI as a new imaging paradigm and provides a summary of current role of DWI in various disease processes.

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Section: Clinical Applications Of Dwimentioning

confidence: 99%

Diffusion weighted imaging: Technique and applications

Baliyan¹,

Das²,

Sharma³

et al. 2016

WJR

294

185

View full text Add to dashboard Cite

show abstract

“…A higher b-value (3,000 sec/mm 2 ) for DWI revealed the specificity for distinguishing neoplasms from bowel inflammation to be increased, with 76% of the positive findings representing neoplasms. DWI has been widely used for the assessment of bowel diseases in recent years; however, the majority of studies have investigated the detection of neoplasms or inflamed bowel loops from normal loops using lower b-values (18,23,(27)(28)(29). However, while the differentiation between bowel inflammation and neoplasms is clinically useful, it remains challenging when lower b values DWI are used, as neoplasms and inflammation are detected with high intensities at b-values between 400-1,200 sec/mm 2 .…”

Section: Discussionmentioning

confidence: 99%

Potential of diffusion‑weighted imaging in magnetic resonance enterography to identify neoplasms in the ileocecal region: Use of ultra‑high b‑value diffusion‑weighted imaging

Feng

Wang

et al. 2019

Oncol Lett

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Patients with chronic inflammatory bowel disease have an increased risk of colorectal cancer, and the differentiation between neoplastic and inflammatory lesions often poses a clinical dilemma. The aim of the present study was to investigate whether diffusion-weighted (DW) magnetic resonance (MR) enterography with ultra-high b-value facilitates the identification of neoplastic lesions in the ileocecal region. A total of 76 patients (22 patients with neoplasms, 26 inflammatory lesions and 28 normal subjects) from 292 cases of suspected bowel disorders were included in the present study. All patients were examined with conventional MR enterography and DW imaging (DWI) with seven different b-values (400, 600, 800, 1,000, 1,200, 1,500 and 3,000 sec/mm 2 ) in a 3T MR scanner. DWI scans with different b-values were analyzed independently by two radiologists for the presence of ileocecal lesions. The signal intensity of the majority of inflammatory lesions and normal bowel segments gradually decreased to the background intensity with increasing b-values; however, neoplastic lesions demonstrated relative hyperintensity compared with the background. In addition, ~76% of the positive findings from b=3,000 sec/mm 2 DWI were neoplasms. In conclusion, a lesion with consistently high signal intensity from DWI images with b-values increasing to 3,000 sec/mm 2 indicated the presence of neoplasms. The results suggested that ultra-high b-value (3,000 sec/mm 2 ) imaging may aid the clinical differentiation of neoplasms from benign conditions.

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“…Furthermore, diffusion-weighted (DW) imaging was not used for MR enterography; however, it has been shown that DW imaging did not improve the performance of MR enterography with gadolinium contrast material in the detection of mesenteric small-bowel tumors (58). Finally, this was a single-center trial, in which the disease prevalence may influence the overall accuracy of CT and MR enterography.…”

Section: Discussionmentioning

confidence: 99%