Diffusion Weighted Magnetic Resonance Imaging of the Breast

Partridge, Savannah C.; McDonald, Elizabeth S.

doi:10.1016/j.mric.2013.04.007

Cited by 152 publications

(62 citation statements)

References 100 publications

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“…Diffusion weighted magnetic resonance imaging (DWI) has shown promise for improving the accuracy and positive predictive value of standard clinical dynamic contrast-enhanced (DCE) MRI 1 . DWI provides indirect information on lesion cellularity through the measurement of water diffusivity by apparent diffusion coefficient (ADC) calculation 2 .…”

Section: Introductionmentioning

confidence: 99%

Diffusion-Weighted Breast Magnetic Resonance Imaging

Rahbar

Kurland²,

Olson³

et al. 2016

Journal of Computer Assisted Tomography

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Objective To determine whether a semi-automated voxel selection technique improves inter-reader reproducibility for breast apparent diffusion coefficient (ADC) measurements. Methods Three readers retrospectively performed ADC measurements of 31 breast lesions (16 malignant, 15 benign) and contralateral normal tissue in 26 women both unassisted (manual method) and assisted by a semi-automated software tool that excludes voxels below a dynamically specified signal intensity threshold. Reproducibility between readers for each technique was assessed by Bland-Altman analysis and concordance correlation coefficients (CCCs). Results Differences between readers’ measured ADCs of lesions were smaller with the semi-automated tool versus the manual method. CCCs for each reader pair were greater with the semi-automated tool for lesions (mean CCC difference= 0.11; CI= 0.04–0.26). For normal tissue, reader agreement was lower than for lesions, and did not differ based on software tools (mean CCC difference= 0.00; 95% CI= −0.14–0.13). Conclusions A semi-automated voxel selection tool can improve inter-reader reproducibility of breast lesion ADC measures.

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Section: Introductionmentioning

confidence: 99%

Diffusion-Weighted Breast Magnetic Resonance Imaging

Rahbar

Kurland²,

Olson³

et al. 2016

Journal of Computer Assisted Tomography

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“…Good quality shimming and suppression of lipid signal are essential to minimize susceptibility and chemical shift artifacts for breast DWI, and use of multichannel RF coil design, parallel imaging, and higher order shimming techniques help to achieve these goals. Strategies to improve SNR include scanning at higher field strength, increasing the number of signal averages, shortening echo time (TE), increasing voxel size, and appropriate choice of b value [4]. …”

Section: Considerations For Clinical Implementationmentioning

confidence: 99%

“…Emerging evidence suggests that diffusion-weighted MRI (DWI) can address some of the limitations of conventional breast MRI by providing complementary information for lesion assessment [4]. Whereas DCE-MRI demonstrates tissue vascularity and provides high sensitivity for cancer detection, DWI reflects the mobility of water molecules diffusing in tissues, revealing tissue organization at the microscopic level.…”

Section: Introductionmentioning

confidence: 99%

DWI in the Assessment of Breast Lesions

Partridge

Amornsiripanitch

2017

Topics in Magnetic Resonance Imaging

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Diffusion-weighted MRI (DWI) holds promise to address some of the shortcomings of routine clinical breast MRI and to expand the capabilities of imaging in breast cancer management. DWI reflects tissue microstructure, and provides unique information to aid in characterization of breast lesions. Potential benefits under investigation include improving diagnostic accuracy and guiding treatment decisions. As a result, DWI is increasingly being incorporated into breast MRI protocols and multicenter trials are underway to validate single institution findings and to establish clinical guidelines. Advancements in DWI acquisition and modeling approaches are helping to improve image quality and extract additional biologic information from breast DWI scans, which may extend diagnostic and prognostic value.

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“…16,17 The b-value is an important parameter in DWI. It is a summary Full paper: Brain multi-b-value DWI in adolescent orphans from AIDS families BJR measure of different pulse sequence parameters and captures the level to which the signal is made sensitive to the diffusion process.…”

Section: Discussionmentioning

confidence: 99%

“…[5][6][7][8][9][10][11][12][13] Advanced MRI techniques include perfusionweighted imaging (PWI), diffusion tensor imaging, MR spectroscopy (MRS) and diffusion-weighted imaging (DWI ) is widely used in the diagnosis, prognosis and treatment assessment of diseases. [16][17][18] Recently, scholars have studied HIV-positive patients with conventional DWI 9,11,13 and have made certain achievements. However, multi-b-value DWI applied to studying HIV-positive patients is much less concerned.…”

Section: Introductionmentioning

confidence: 99%

Application of brain multi-b-value diffusion-weighted imaging (DWI) in adolescent orphans from AIDS families

Jiang

Zhong

Zhou

et al. 2016

BJR

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Objective: To evaluate the application value of multib-value diffusion-weighted imaging (DWI) with monoexponential model and stretched-exponential model in the diagnosis of HIV-positive patients. Methods: 50, 150, 200, 400, 600, 800 s mm 22) DWI was performed in 23 adolescent orphans from AIDS families, including 15 HIV-positive subjects and 8 HIV-negative healthy subjects. Apparent diffusion coefficient (ADC) values were fitted by monoexponential model; distribution diffusion coefficient (DDC) values and heterogeneity index (a) values were fitted by stretched-exponential model in bilateral basal ganglia, then non-parametric tests were performed. Results: The signal intensity attenuation in multi-b-value DWI could be well described by both mono-exponential model and stretched-exponential model. In the left basal ganglia, mean a-values in HIV-positive subjects (a 5 0.848 6 0.068) were significantly lower than that in healthy subjects (a 5 0.923 6 0.050, p 5 0.013). There was no statistical difference of a-values between HIV-positive subjects and healthy control subjects in the right basal ganglia. Apart from these, there were also no statistical differences of DDC values or ADC values between two groups in bilateral basal ganglia (all p . , we can see stretched-exponential model DWI can provide more information than mono-exponential model DWI. Advances in knowledge: Multi-b-value DWI was performed in subjects with HIV. DWI measurements could be neuroimaging biomarkers of cerebral injury in the course of HIV infection.

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Diffusion Weighted Magnetic Resonance Imaging of the Breast

Cited by 152 publications

References 100 publications

Diffusion-Weighted Breast Magnetic Resonance Imaging

Diffusion-Weighted Breast Magnetic Resonance Imaging

DWI in the Assessment of Breast Lesions

Application of brain multi-b-value diffusion-weighted imaging (DWI) in adolescent orphans from AIDS families

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