“…Animal studies notably showed that axial and radial diffusivities are good predictors of axonal loss and demyelination, respectively (Budde et al, 2007). DTI has been applied to assess the severity of the spinal cord injury (Agosta et al, 2007;Budde et al, 2007;Cohen-Adad et al, 2008a;DeBoy et al, 2007;Deo et al, 2006;Ducreux et al, 2007;Ellingson et al, 2008;Fujiyoshi et al, 2007;Kim et al, 2007;Lammertse et al, 2007;Nevo et al, 2001;Ohgiya et al, 2007;Plank et al, 2007;Ries et al, 2000;Schwartz et al, 2005;Shen et al, 2007;Thurnher and Bammer, 2006;Valsasina et al, 2005;Vargas et al, 2007). As an extension to DTI, high angular resolution diffusion imaging (HARDI) and Q-Ball imaging (QBI) can represent more than one diffusion direction, thereby alleviating limitations of the diffusion tensor in presence of crossing fibers (Tuch, 2004).…”