Diffusion-weighted MR imaging for detection of extrahepatic cholangiocarcinoma

Cui, Xing-Yu; Chen, Hongwei; Cai, Song Qi; Bao, Jinsong; Tang, Qikai; Wu, Li-Yuan; Fang, Xiangming

doi:10.1016/j.ejrad.2011.12.040

Cited by 35 publications

(14 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[26]. However, ADC values were reported in the aggregate for the two types of cholangiocarcinoma without subgroup analysis so that the specific ADC value of hilar cholangiocarcinomas was not reported [26]. In our study, the ADC value of cholangiocarcinomas was significantly lower than that of the apparently normal hepatic parenchyma, which is consistent with prior studies who uniformly reported that malignant hepatic tumors have lower ADC values than the normal hepatic parenchyma 14].…”

Section: Discussionsupporting

confidence: 92%

See 1 more Smart Citation

Intrahepatic and hilar mass-forming cholangiocarcinoma: Qualitative and quantitative evaluation with diffusion-weighted MR imaging

Fattach

Dohan

Guerrache

et al. 2015

European Journal of Radiology

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 92%

“…* Conspicuity was semi-quantitatively assessed using a five point scale (1-5). [26]. However, ADC values were reported in the aggregate for the two types of cholangiocarcinoma without subgroup analysis so that the specific ADC value of hilar cholangiocarcinomas was not reported [26].…”

Section: Discussionmentioning

confidence: 96%

Intrahepatic and hilar mass-forming cholangiocarcinoma: Qualitative and quantitative evaluation with diffusion-weighted MR imaging

Fattach

Dohan

Guerrache

et al. 2015

European Journal of Radiology

View full text Add to dashboard Cite

“…Few experiences, mainly focused to a qualitative visual assessment of DW images, have been reported regarding cholangiocarcinoma (CCC). Cui et al [41] found an inverse correlation between the pathological grade and ADC values; Park et al [42] reported that the addition of DWI to conventional sequences might improve the pre-operative assessment of hilar CCC, increasing the sensitivity for the evaluation of tumor extent along the bile ducts and liver invasion, thus improving T stage, a parameter that is directly related to prognosis.…”

Section: Primary Liver Tumorsmentioning

confidence: 99%

Prognostication and response assessment in liver and pancreatic tumors: The new imaging

Robertis¹,

Martini²,

Demozzi³

et al. 2015

WJG

View full text Add to dashboard Cite

Diffusion-weighted imaging (DWI), dynamic contrastenhanced magnetic resonance imaging (DCE-MRI) and perfusion computed tomography (CT) are technical improvements of morphologic imaging that can evaluate functional properties of hepato-bilio-pancreatic tumors during conventional MRI or CT examinations. Nevertheless, the term "functional imaging" is commonly used to describe molecular imaging techniques, as positron emission tomography (PET) CT/MRI, which still represent the most widely used methods for the evaluation of functional properties of solid neoplasms; unlike PET or single photon emission computed tomography, functional imaging techniques applied to conventional MRI/CT examinations do not require the administration of radiolabeled drugs or specific equipments. Moreover, DWI and DCE-MRI can be performed during the same session, thus providing a comprehensive "one-step" morphological and functional evaluation of hepato-bilio-pancreatic tumors. Literature data reveal that functional imaging techniques could be proposed for the evaluation of these tumors before treatment, given that they may improve staging and predict prognosis or clinical outcome. Microscopic changes within neoplastic tissues induced by treatments can be detected and quantified with functional imaging, therefore these techniques could be used also for posttreatment assessment, even at an early stage. or altered cellular membranes will present diffusion restriction, which is depicted as signal hyperintensity areas on high b-value DW images and hypointensity on the apparent diffusion coefficient (ADC) maps; ADC measurement can also quantify water molecules' diffusion. As dedifferentiation or therapies may induce microscopic changes in neoplastic tissues that could modify water molecules' diffusion, DWI can distinguish between different degrees of malignancy and can be also proposed for post-treatment monitoring. Moreover, DWI can be performed in a single session with DCE-MRI, thus providing a comprehensive "one-step" morphological and functional evaluation of hepatobilio-pancreatic tumors.Perfusion imaging techniques evaluate changes in signal intensity (DCE-MRI) or density (pCT) after contrast medium injection, being therefore able to assess microvascularization through the evaluation of the dynamics of contrast medium distribution from vessels to the neoplastic tissue. Perfusion parameters are therefore theoretically good candidates for the evaluation of microscopic vascular differences between lesions with different pathological grade and for the assessment of treatment response, especially after chemoembolization or during treatments with antiangiogenic drugs.This editorial analyzes up-to-date literature data regarding the application of functional imaging techniques, apart from molecular imaging, to hepatic and pancreatic tumors, with particular emphasis on correlations to pathological features, prognostic stratification and therapeutic response assessment. FUNCTIONAL IMAGING TECHNIQUES: TECHNICAL BASESIn 1965 Stejskal and Tanne...

show abstract

“…DW-MRI at high b values is a reliable predictor for a malignant bile stricture and can improve sensitivity of MRCP due to its sensitivity in appraising hypercellularity [5,11,[14][15][16]; nevertheless care must be taken since inflammatory processes can also be hyperintense on DW-MRI [15,16]. Moreover DW-MRI may not be discriminatory in cases of well differentiated neoplasms or for small tumors, and image quality may suffer from artifacts that induce signal loss [11].…”

Section: Mri Findings Odds Ratio (95% Ci) Pmentioning

confidence: 99%

“…Moreover DW-MRI may not be discriminatory in cases of well differentiated neoplasms or for small tumors, and image quality may suffer from artifacts that induce signal loss [11]. …”

Section: Mri Findings Odds Ratio (95% Ci) Pmentioning

confidence: 99%

MRI system scoring for differentiation of malignant versus benign stricture of the common bile duct

Savastano¹,

Ld²,

Cuoco³

et al. 2016

J Radiol Imaging.

View full text Add to dashboard Cite

Diffusion-weighted MR imaging for detection of extrahepatic cholangiocarcinoma

Cited by 35 publications

References 17 publications

Intrahepatic and hilar mass-forming cholangiocarcinoma: Qualitative and quantitative evaluation with diffusion-weighted MR imaging

Intrahepatic and hilar mass-forming cholangiocarcinoma: Qualitative and quantitative evaluation with diffusion-weighted MR imaging

Prognostication and response assessment in liver and pancreatic tumors: The new imaging

MRI system scoring for differentiation of malignant versus benign stricture of the common bile duct

Contact Info

Product

Resources

About