Diffusion-Weighted MR Imaging for Differentiation of Benign Fracture Edema and Tumor Infiltration of the Vertebral Body

Abstract

Diffusion-weighted spin-echo, fat-suppressed spin-echo, and stimulated-echo sequences are equally suitable for imaging of the spine. Calculation of signal attenuation and observation of signal characteristics allowed differentiation of benign fracture edema and tumor infiltration and provided excellent distinction between benign and malignant vertebral fractures in our series.

The value of apparent diffusion coefficient measurements in the differential diagnosis of vertebral bone marrow lesions

“…Some studies have been able to differentiate benign acute compression fractures from malign induced compression fractures according to ADC values (3,4,(13)(14)(15)(16). In a comparatively small number of surveys, ADC values have been studied in discriminating the infectious lesions from the malign lesions (4,5,17).…”

Improved Detection of Skull Metastasis with Diffusion-Weighted MR Imaging

“…3,4 DWI has also been used for a wide range of other pathologies including metastasis to vertebral bodies, [5][6][7][8][9][10][11][12][13][14][15][16][17] though there has been controversy on this subject. 18,19 DWI may be helpful to differentiate pathologic compression fractures related to metastases from benign osteoporotic compression fractures.…”

Automatic segmentation of subcutaneous mouse tumors by multiparametric MR analysis based on endogenous contrast

“…In a future study, the accuracy of manual tumor delineation could be improved by inclusion of diffusion-weighted images as a visual reference. The contrast between tumor and edematous tissue is usually better on diffusion-weighted images than on T 2 -weighted images, because of the large difference between apparent diffusion coefficient of water in tumor tissue and edema [30]. In addition, manual segmentation could also be performed on contrast-enhanced T 1 -weighted images.…”