Diffusion-weighted MRI: In differential diagnosis of liver masses

Ergelen, Rabia; Şahin, Cennet; Bal, Hacer; Tüney, Davut

doi:10.5472/mmjoa.2903.02

Cited by 4 publications

(3 citation statements)

References 9 publications

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“…Battal, 33 Testa, 34 and others 35–40 agreed that DWI could differentiate malignant from benign lesions (78% accuracy for all benign lesions and 71% for solid liver lesions in Testa's study 34 ). This was because space‐occupying liver lesions presented different DWI and ADC values on imaging.…”

Section: Diffusion‐weighted Image–magnetic Resonance Imagingmentioning

confidence: 79%

“…Several studies reported DWI to be superior compared with T2WI for focal lesion detection and image quality, 5,36,39,40 as well as having enhanced sensitivity to detecting metastatic cancer rather than HCCs. 40 These studies also stated that DWI with a low b-value showed better lesion detection performance than T2WI.…”

Section: Differentiation Of Malignant and Benign Lesions Using Diffus...mentioning

confidence: 99%

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The clinical value of dual‐energy computed tomography and diffusion‐weighted imaging in the context of liver cancer: A narrative review

Fan

Chu

Wang

et al. 2022

J of Clinical Ultrasound

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The dual‐energy computed tomography (DECT) and diffusion‐weighted magnetic resonance imaging (DWI‐MRI) are used to diagnose liver cancer. The clinical value of these two examination methods needs to be further summarized. We collected and summarized relevant literature published from 2011 to 2021. The diagnostic performance of DECT was assessed between conventional computed tomography and DWI‐MRI. DWI‐MRI had a 69% sensitivity for detecting small hepatocellular carcinoma (HCC) lesions and a 60% diagnostic specificity for differentiating between types of HCC lesions. DECT had a sensitivity to small liver lesions (<1 cm) of 69%, and the diagnostic specificity for HCC and metastasis was about 60%. DWI was more sensitive (90.3% vs. 74.9%) and accurate (91.9% vs. 76.9%) in diagnosing HCC compared with conventional MRI sequencing. With the aid of contrast media, DWI‐MRI had 90.0% specificity for detecting small HCCs (smaller than 1 cm). Furthermore, DWI‐MRI not only provided physicians with valuable diagnostic information but also delivered histological grading information, with 78% accuracy for all benign lesions and 71% for solid lesions. DECT had relatively high sensitivity and required a lower contrast medium dose. With standardized quantitative parameters, it can be an extremely useful tool for HCC surveillance. DWI‐MRI is the preferred imaging process as it produces high‐contrast images for supporting an early diagnosis (high sensitivity and specificity) and provides histological information using non‐ionizing radiation.

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Section: Diffusion‐weighted Image–magnetic Resonance Imagingmentioning

confidence: 79%

Section: Differentiation Of Malignant and Benign Lesions Using Diffus...mentioning

confidence: 99%

The clinical value of dual‐energy computed tomography and diffusion‐weighted imaging in the context of liver cancer: A narrative review

Fan

Chu

Wang

et al. 2022

J of Clinical Ultrasound

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“…Ergelen et al (23) reported that hemangiomas and metastatic masses differed statistically significantly. With a threshold ADC value of 1.33x10 -3 mm 2 /s, lesions could be distinguished with a sensitivity and specificity of 81% and 86%, respectively, according to ROC analysis (P <0.001).…”

Section: Discussionmentioning

confidence: 99%

Differentiation Between Hepatic Hemangioma and Metastasis by Diffusion Weighted MRI

Helmy¹,

Latif²,

Sultan³

2022

The Egyptian Journal of Hospital Medicine

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Background: Diagnosis of hepatic focal lesions could be done by magnetic resonance imaging (MRI) study especially when diffusion-weighted magnetic resonance imaging (DWI) is included in the imaging protocol with apparent diffusion coefficient (ADC) quantification. Several studies have demonstrated that combining DWI with ADC measurement plays an important role in the detection and characterization of hepatic focal lesions and differentiating hemangioma from hepatic deposits. Objective: The current study aimed at evaluation of the role of diffusion weighted imaging differentiating between hepatic hemangioma and metastasis (1-4 lesions in number) by diffusion weighted MRI in patient pathologically proved to have primary malignancy. Patient and methods: Fifty cases were included; patients referred to Radiology Department of Mansoura University Hospital. There were 33 females and 17 male patients with age ranged from 26 to 82 years. All patients were subjected to proper history taking and DWI MRI. This study was using a 1.5 T Philips Ingenia MRI scanner. Results: ADC had significantly lower values in patients with metastatic hepatic lesions with mean ADC 0.93 (SD 0.21) x10 -3 mm 2 /sec. ADC had significantly higher values in patients with hemangioma with mean ADC 1.96 (SD 0.31) x10 -3 mm 2 /sec. The mean ADC value in the metastatic group was statistically significantly lower compared to the hemangioma group. ADC had sensitivity and specificity of 100 % and 95.8% respectively, and an accuracy of 97.4% in differentiating between hemangioma and metastasis cases, when a cut-off value of 1.55 x 10-3mm2/s was applied. Conclusion: Combined qualitative and quantitative analysis of DWI and ADC values respectively can help in differentiation between hepatic hemangioma and metastatic deposits. Using DWI and ADC in conjunction with conventional imaging found to be a simple and non-invasive tool that aid in differentiation between hepatic hemangioma and metastatic deposits.

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Diagnostic ability of diffusion-weighted imaging using echo planar imaging with compressed SENSE (EPICS) for differentiating hepatic hemangioma and liver metastasis

Kaga,

Noda,

Asano

et al. 2023

European Journal of Radiology

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Diffusion-weighted MRI: In differential diagnosis of liver masses

Cited by 4 publications

References 9 publications

The clinical value of dual‐energy computed tomography and diffusion‐weighted imaging in the context of liver cancer: A narrative review

The clinical value of dual‐energy computed tomography and diffusion‐weighted imaging in the context of liver cancer: A narrative review

Differentiation Between Hepatic Hemangioma and Metastasis by Diffusion Weighted MRI

Diagnostic ability of diffusion-weighted imaging using echo planar imaging with compressed SENSE (EPICS) for differentiating hepatic hemangioma and liver metastasis

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