Digestion and Absorption After Massive Resection of the Small Intestine

Althausen, T. L.; Doig, R.K.; Uyeyama, Kahn; Weiden, Sara

doi:10.1016/s0016-5085(19)36599-0

Cited by 79 publications

(19 citation statements)

References 11 publications

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“…The large percentage of the dose excreted by this patient is difficult at first to reconcile with her normal faecal nitrogen excretion. This discrepancy is again likely to be due to the use of a fluid oral test dose which might be expected to pass rapidly through the small amount of residual small intestine, whereas food protein, as has been demonstrated after intestinal resection (Althausen, Uyeyama, and Simpson, 1949), may behave differently.…”

Section: Discussionmentioning

confidence: 99%

On the use of tritium-labelled albumin for studies of intestinal absorption

Kn¹,

Stewart²,

Evans³

et al. 1964

Gut

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West Middlesex Hospital, and the Radiochemical Centre, Amersham EDITORIAL SYNOPSIS Human serum albumin has been successfully labelled with tritium. It is considerably denatured in the process and has a shorter half life when given intravenously than 131-labelled albumin. Nevertheless it is satisfactory for absorption studies, although not for turnover observations. These studies on absorption in control subjects and in patients with intestinal malabsorption indicate that the excreted radioactivity may have been derived from endogenous sources rather than from the results of malabsorption alone.In recent years, albumin labelled with 1311 has been increasingly used as a method for studying protein absorption

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Section: Discussionmentioning

confidence: 99%

On the use of tritium-labelled albumin for studies of intestinal absorption

Kn¹,

Stewart²,

Evans³

et al. 1964

Gut

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“…The wide-ranging and variable effects of extensive resections of small intestine have been discussed in many excellent studies and reviews in the last decade (Althausen, Doig, Uyeyama, and Weiden, 1950;Jackson andLinder, 1951, 1955 his 'ideal' weight of 10.3 kg. equivalent to 3 5 g. of es and period III was five days.…”

Section: Discussionmentioning

confidence: 99%

A study of malabsorption after resection of the entire jejunum and the proximal half of the ileum

Clayton¹,

Cotton²

1961

Gut

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SYNOPSIS Biochemical, haematological, and radiological investigations are reported in a young child in whom nearly 80% of the small intestine was resected. The prognosis in a child after such extensive resection is probably better than in an adult, as natural growth can still occur with the expectation of greater adaptability as well as of increased length of the remaining segments.The supreme role of the small intestine in digestion and absorption makes it an indispensable organ. Elaboration of the functions of its several parts is of considerable importance because of its involvement at different levels by a variety of diseases and anatomical lesions. Although special techniques (Borgstrom, Dahlqvist, Lundh, and Sjovall, 1957;Blomstrand, 1958;Cox, Meynell, Cooke, and Gaddie, 1958; Booth and Mollin, 1959) (Fig. 1). He was at that time a bright, underweight child with a protuberant abdomen. His diet was similar to that of a 6-month-old infant, and it was noted that milk feeds tended to pass through quickly. He was subject to attacks of prostration with episodes of vomiting and diarrhoea.It was at that stage, two months post-operatively, that our investigations began. His haemoglobin was 88 % (12-8 g.), red and white blood cell counts were normal, reticulocytes 0-6 %, and prothrombin time normal.

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“…This may be due to disease in the remaining portions of the gut-for example, Crohn's disease-or formation of blind loops, but Jackson (1958) believes that in the absence of complications the resection of less than two-thirds of the small bowel causes no serious metabolic disturbances. After massive resection large losses of faecal nitrogen occur; these may be a a s 50% of the nitrogen intak and amino-acid tolerance tests are abnormal (Altha sen, Uyeyama and Simpson, 1949). Perhaps the most striking feature of reported cases is that within a few months of massive resection, bowel movements, initially 20 or so a day, return to normal and patients often regain their pre-operative body weights.…”

Section: Secretion On Protein Absorptionmentioning

confidence: 99%

Some Aspects of Protein Digestion and Absorption in Health and Disease

Crane

1961

Postgraduate Medical Journal

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Digestion and Absorption After Massive Resection of the Small Intestine

Cited by 79 publications

References 11 publications

On the use of tritium-labelled albumin for studies of intestinal absorption

On the use of tritium-labelled albumin for studies of intestinal absorption

A study of malabsorption after resection of the entire jejunum and the proximal half of the ileum

Some Aspects of Protein Digestion and Absorption in Health and Disease

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