Digestive comorbidity in patients with rheumatic diseases: Not only NSAID-induced gastropathy

Каратеев, А. Е.; Гонтаренко, Н. В.; Цурган, А. В.

doi:10.14412/1995-4484-2016-382-389

Cited by 5 publications

(2 citation statements)

References 46 publications

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“…Наиболее часто НПВП назначают для симптоматической коррекции проявлений ревматологических заболеваний [1156]. Почти 2/3 всех случаев поражения ЖКТ, ассоциированного с приемом НПВП, приходится на тонкую кишку 109 [1157,1158].…”

Section: наиболее частые варианты коморбидности болезней тонкой и тол...unclassified

“…У пациентов, регулярно принимавших НПВП не менее 2 нед., при эндоскопическом исследовании органов ЖКТ выявлено частое сочетание НПВП-индуцированного поражения различных отделов ЖКТ (эрозиии, язвы, геморрагии, стриктуры, признаки кровотечения): гастроэнтеропатия у 48,9%, гастроколопатия у 28,6%, гастроэнтероколопатия у 20,4% [1158,1160].…”

Section: наиболее частые варианты коморбидности болезней тонкой и тол...unclassified

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Comorbidity of patients with noncommunicable diseases in general practice. Eurasian guidelines

Drapkina,

Kontsevaya,

Kalinina

et al. 2024

Cardiovasc Ther Prev

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Section: наиболее частые варианты коморбидности болезней тонкой и тол...unclassified

Comorbidity of patients with noncommunicable diseases in general practice. Eurasian guidelines

Drapkina,

Kontsevaya,

Kalinina

et al. 2024

Cardiovasc Ther Prev

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Chronic hepatitis B in hospitalized rheumatologic patients: problems of screening and reactivation of infection

Gridneva,

Aronova,

Belov

2023

Sovremennaâ revmatologiâ

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Objective: to evaluate the completeness of screening for hepatitis B virus (HBV) infection in HBsAg-positive patients admitted to a rheumatology hospital and to follow the history of HBV reactivation/seroversion during antirheumatic therapy. Material and methods. The results of initial and repeated (if applicable) hospitalizations were analyzed in 80 patients with rheumatic diseases (RD), including 55 (69%) women and 25 (31 %) men, with Australian surface antigen (HBsAg), admitted to the V.A. Nasonova Institute of Rheumatology from January 1, 2020 to July 20, 2022 (30 months). Results and discussion. The total number of hospitalizations to the clinic during the observation period, including repeat admissions, was 13,681. The number of hospitalizations in 80 patients with HBV infection during the observation period, including repeat admissions, was 144, of which for systemic vasculitis – 6 (8 %), other systemic connective tissue diseases – 16 (20 %), osteoarthritis and post-traumatic changes of joints – 14 (15 %), inflammatory joint diseases – 42 (54 %). Cases of HBV reactivation/seroverion, both in anamnesis and during observation, were detected in 9 (11 %) patients, and most frequently (n = 5) they were registered during methotrexate therapy. Conclusion. HBV infection in patients with RD leads to significant difficulties in the selection of drug therapy, due to the risk of reactivation of the infection. The results obtained indicate incomplete screening of patients with RD for HBV infection during the preclinical phase. Further investigation is needed to develop clear recommendations for the management of patients with RD infected with HBV.

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Patient with polymyalgia rheumatica — how to prevent gastrointestinal damage?

Кудина¹,

Самкова²,

Ларина³

2020

jour

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Basis. The problem of multimorbidity and related polypragmasia is highly relevant for health practitioners. Providing treatment a doctor should keep in mind itsall possible negative consequences that might exacerbate other diseases. One of the most current problems of modern pharmacotherapy is the development of gastropatia and other gastrointestinal lesions because of drug intake. It is extremely important for rheumatologic patients, especially elderly ones, due to side effects of nonsteroidal anti-inflammatory drugs and glucocorticoids. Reasonable approach to the prescription of this therapy and side effects prevention is a significant factor of the preventive work of the therapist and the general practitioner of the outpatient service. In patients with rheumatic polymyalgia we showed an approach to long-term treatment of corticosteroids in elderly patients, the aim of which is to achieve a stable remission of the disease and to minimize the undesirable effect of the medication on the gastrointestinal tract.Aim. Provide an algorithm for the approach to identifying the risk factors of medicinal gastrointestinal lesions and methods for their prevention.Material and methods. We analyzed literature sources, including Russian guidelines over the last 10 years.Results. In the article we present an algorithm for detecting the risk of developing gastrointestinal tract lesions against the background of corticosteroid therapy in elderly patients and ways of preventing it.Conclusion. The prevention of unwanted drug reactions is an important aspect of a doctor’s work, especially in the treatment of elderly patients. The presented algorithm for identification of risk groups and prevention of side effects is intended to help the practical doctor in working with this category of patients.

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Digestive comorbidity in patients with rheumatic diseases: Not only NSAID-induced gastropathy

Cited by 5 publications

References 46 publications

Comorbidity of patients with noncommunicable diseases in general practice. Eurasian guidelines

Comorbidity of patients with noncommunicable diseases in general practice. Eurasian guidelines

Chronic hepatitis B in hospitalized rheumatologic patients: problems of screening and reactivation of infection

Patient with polymyalgia rheumatica — how to prevent gastrointestinal damage?

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