In the international arena, the use of technology as a tool for accessing information but also for creating content and sharing that generated content is beginning to gain importance. The main objective of this article is to provide knowledge of the new tools used in the international context in cultural access and to facilitate understanding, use and appropriate improvements with respect to cultural access for persons with disabilities. The methodology used, we have carried out a systematic review with a selection of 410 examined articles finally selected 34 articles covering from 2000 to 2020. Ten databases have been used in the exhaustive search and selection: 1Findr, Semantic Scholar, Scopus, Google Scholar, Microsoft Academy Search, Wos, IEEE Xplorer, Miar, Mendeley, Science Direct. The results obtained in the selected studies are characterized by their international scope, in the case of digital creation applications, virtual environments, and RA. Among the conclusions obtained, it is evident the need for collaboration between museums and institutions, to achieve significant progress in awareness, education, and access for all. Promote the development of accessibility plans, the exchange of information on actions at the international level, along with the means necessary to achieve better access to cultural spaces.