The preface summarizes six contributions within a special issue of Information Services and Use in tribute to Andrew Pleasant, Ph.D., 1962–2022. Five topic-oriented manuscripts within the special issue are devoted to health literacy and health communication issues during the COVID-19 pandemic. A sixth paper focuses on Dr. Pleasant’s career and contributions. In addition to manuscript summaries, the preface introduces two health literacy/health mass communication topics: a constructive response to the ‘infodemic’; and the value of health narratives. These topics were of interest to Dr. Pleasant during the pandemic and augment some of the issues raised within the special tribute issue’s other contributions.