Digital PCR to Measure SARS-CoV-2 RNA, Variants, and Outcomes in Youth
Diego R Hijano,
Jose A Ferrolino,
Zhengming Gu
et al.
Abstract:Background
The role of SARS-CoV-2 viral load in predicting contagiousness, disease severity, transmissibility, and clinical decision-making continues to be an area of great interest. However, most studies have been in adults and have evaluated SARS-CoV-2 loads using cycle thresholds (Ct) values, which are not standardized preventing consistent interpretation critical to understanding clinical impact and utility. Here, a quantitative SARS-CoV-2 reverse-transcription digital PCR (RT-dPCR) assay… Show more
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