Digital radiomorphometric analysis of the frontal sinus and assessment of the relation between persistent metopic suture and frontal sinus development

Nikolova, Silviya; Toneva, Diana; Georgiev, Ivan; Lazarov, Nikolai

doi:10.1002/ajpa.23375

Cited by 34 publications

(48 citation statements)

References 52 publications

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“…The FS aplasia has been reported to vary from 0.7 to 62% in different population groups [4,21,23,28,31,[34][35][36][37][38][39]. The unilateral aplasia of the FS has been found to be more common than the considerably rarer bilateral one [4,21,40]. The side prevalence varies in different population groups, but right-sided aplasia seems to be more frequent [4,8,21].…”

Section: Fs Aplasiamentioning

confidence: 99%

“…The unilateral aplasia of the FS has been found to be more common than the considerably rarer bilateral one [4,21,40]. The side prevalence varies in different population groups, but right-sided aplasia seems to be more frequent [4,8,21]. There have also been reported cases of agenetic FS, where the contralateral sinus expands and crosses the midline towards the agenetic side and mimics the presence of bilateral frontal sinuses [41].…”

Section: Fs Aplasiamentioning

confidence: 99%

“…The different partitions and layers of the frontal bone develop and maturate simultaneously, but independently from one another in accordance with the functional demands of the related soft tissues/cavities [1]. It has been observed that in cases of persistent metopic suture (MS), the frontal sinus (FS) develops separately on either side of the suture, as well as the MS precludes the likelihood of development of the sinus beyond the median plane [2][3][4]. Nevertheless, the supposed influence of metopism on the FS development has not been synonymous.…”

Section: Introductionmentioning

confidence: 99%

“…Some authors did not find a significant correlation between metopism and the underdevelopment of the FS [5][6][7][8], which leads to the assertion that the association of these variations is rather random. Other studies, however, revealed a tendency of MS persistence to be significantly related to the FS underdevelopment, including both FS aplasia and hypoplasia [4,[9][10][11][12][13][14]. Both the MS persistence and FS underdevelopment are not exceptional variations, but the correlation between them is intricate.…”

Section: Introductionmentioning

confidence: 99%

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Relation between Metopic Suture Persistence and Frontal Sinus Development

Nikolova¹,

Toneva²,

Georgiev³

et al. 2019

Challenging Issues on Paranasal Sinuses

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The frontal bone develops as two halves, which further unite in a single bone by the closure of the mid-sagittal metopic suture, typically by the end of the first postnatal year. The frontal sinus begins to expand into the orbital and vertical plates of the frontal bone postnatally and reaches the level of the nasion by the fourth year of age. At this time, the metopic suture is usually entirely closed. However, in the cases of failed closure of the metopic suture, its relationship to the frontal sinus development is still obscure. Here, we review the relevant literature and discuss the frontal bone development and maturation, from the viewpoint of the frontal sinus pneumatization in relation to the metopic craniosynostosis and failed closure of the metopic suture. The peculiar to the metopic skulls frontal bone configuration is rather an expression of the underlying neural mass demands than a consequence of the metopic suture persistence. Furthermore, the persistent metopic suture is frequently associated with a frontal sinus underdevelopment. It seems that the metopic suture does not inhibit the frontal sinus pneumatization itself, but rather both traits are an expression or an aftereffect of a certain condition during the early development.

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Section: Fs Aplasiamentioning

confidence: 99%

Section: Fs Aplasiamentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Relation between Metopic Suture Persistence and Frontal Sinus Development

Nikolova¹,

Toneva²,

Georgiev³

et al. 2019

Challenging Issues on Paranasal Sinuses

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“…Industrial micro‐CT (μCT) systems are a versatile, powerful, nondestructive, and accurate modality. They generate volumetric images with spatial resolution high enough to allow a reliable qualitative and quantitative investigation of calcified tissues at a trabecular level (Anderson et al, ; Feldkamp, Goldstein, Parfitt, Jesion, & Kleerekoper, ; Harth et al, ; Kuhn, Goldstein, Feldkamp, Goulet, & Jesion, ; Nikolova et al, ; Nikolova, Toneva, Georgiev, Dandov, & Lazarov, ; Nikolova, Toneva, Georgiev, & Lazarov, ; Nikolova, Toneva, Georgiev, Yordanov, & Lazarov, ; Obert et al, ; Ozaki et al, ; Sherick, Buchman, Goulet, & Goldstein, ).…”

Section: Introductionmentioning

confidence: 99%

Sagittal suture maturation: Morphological reorganization, relation to aging, and reliability as an age‐at‐death indicator

Nikolova

Toneva

Georgiev

et al. 2019

American J Phys Anthropol

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Objectives: The sagittal suture (SS) is assumed to be an initial site for the commencement of cranial suture closure as well as the most frequent spot of isolated craniosynostosis. The present study aimed to inspect the reorganization of the SS at the microlevel to assess the relation between its closure and aging and to establish whether it could be used as a reliable indicator in age-at-death prediction. Materials and methods:The SS was investigated in 68 dry contemporary adult male skulls of known age-at-death. An additional series of 20 skulls was used for verification. The skulls were scanned using a micro-computed tomography system. The SS closure degree was assessed along the three bone layers on cross-sectional tomograms by using a scoring scale. Results:In the entirely open SS, the bone edges consist of compact bone and are widely separated. With SS maturation, the bone edges come into contact, and the remodeling process leads to a decrease in the sutural area and bone homogenization across all three layers. SS closure is an irregular process roughly related to aging, beginning in the early 20s, reaching its peak at about 30 years of age and abating in the late 40s.Discussion: Although related to aging, SS closure is not a simple function of it. Rather, the underlying factors inducing and managing this process are multifaceted and complex. Although the etiology of SS maturation remains unclear, it is reasonable to use SS closure cautiously and only as a supportive method for age prediction. K E Y W O R D Sage prediction, cranial suture biology, dry skulls, industrial μCT scanning, regression models

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Variation, sexual dimorphism, and enlargement of the frontal sinus with age in adult South Africans

Greening,

Hernandez,

Mongle

et al. 2024

American Journal of Biological Anthropology

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ObjectivesTo document frontal sinus volume (FSV) in a sample of sub‐Saharan Africans with a view to evaluating claims that such populations exhibit comparatively small sinuses. This study also addresses questions related to sexual dimorphism, incidence of sinus aplasia, and the possibility that FSV continues to increase through adulthood.Materials and methodsFSV was measured from CT scans of adult crania from the Dart Collection. Sex and age were known for each individual. Linear cranial dimensions were used to compute a geometric mean from which a scaled FSV was computed for each cranium.ResultsFSV does not differ significantly between sexes, but females exhibit a higher incidence of aplasia. There is considerable variation in FSV in this sample, with the average ranking among the higher means reported for other population samples. The incidence of FS aplasia falls within the range of values recorded for other population samples. Although our study is cross‐sectional rather than longitudinal, there is strong evidence that FSV continues to increase with age throughout adulthood.DiscussionThe FSV mean of our sample contradicts the notion that sub‐Saharan Africans possess small sinuses. In a global context, geography (climate and altitude) does not appear to be related to FSV. The absence of sexual dimorphism in our sample is unexpected, as significant dimorphism has been reported for most other population samples. Our results support other indications that the frontal sinus continues to expand throughout adulthood, especially in females, and that it is likely due to bone resorption.

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Digital radiomorphometric analysis of the frontal sinus and assessment of the relation between persistent metopic suture and frontal sinus development

Cited by 34 publications

References 52 publications

Relation between Metopic Suture Persistence and Frontal Sinus Development

Relation between Metopic Suture Persistence and Frontal Sinus Development

Sagittal suture maturation: Morphological reorganization, relation to aging, and reliability as an age‐at‐death indicator

Variation, sexual dimorphism, and enlargement of the frontal sinus with age in adult South Africans

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