Dignitätsbeurteilung fokaler Leberläsionen mit der kontrastverstärkten MRT mit SHU 555 A im Vergleich zur nativen MRT und zur Mehrzeilen-Detektor-Spiral-CT

Jung, Geun Yong; Poll, L. W.; Cohnen, Mathias; A, Saleh; Vogler, H; Wettstein, Mathias; Willers, Reinhart; Mödder, Ulrich; Ja, Koch

doi:10.1055/s-2005-858627

Cited by 5 publications

(1 citation statement)

References 8 publications

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“…Fehlen die nötigen Vorinformationen, kann keine definitive Diagnose gestellt werden, was den "Fall" für eine diagnostische Studie wertlos macht [39]. Die rasche technische Entwicklung bedingt es, dass die Ergebnisse von evidenzbasierten Studien schon wieder überholt sein können, wenn in der Zwischenzeit neue Technologie verfügbar ist.…”

Section: Evidenzbasierte Interventionelle Radiologie Und Radiologischunclassified

Evidenzbasierte Radiologie: Ein neuer Ansatz zur Bewertung von klinisch angewandter radiologischer Diagnostik und Therapie

Puig¹,

Felder-Puig

2006

Fortschr Röntgenstr

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Over the last several years, the concept and methodology of Evidence-Based Medicine (EBM) have received significant attention in the scientific community. However, compared to therapeutic medical disciplines, EBM-based radiological publications are still underrepresented. This article summarizes the principles of EBM and discusses the possibilities of their application in radiology. The presented topics include the critical appraisal of studies on the basis on EBM principles, the explanation of EBM-relevant statistical outcome parameters (e. g., "likelihood ratio" for diagnostic and "number needed to treat" for interventional procedures), as well as the problems facing evidence-based radiology. Evidence-based evaluation of radiological procedures does not only address aspects of cost-effectiveness, but is also particularly helpful in identifying patient-specific usefulness. Therefore it should become an integral part of radiologist training.

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Section: Evidenzbasierte Interventionelle Radiologie Und Radiologischunclassified

Evidenzbasierte Radiologie: Ein neuer Ansatz zur Bewertung von klinisch angewandter radiologischer Diagnostik und Therapie

Puig¹,

Felder-Puig

2006

Fortschr Röntgenstr

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Computed tomography for the diagnosis of hepatocellular carcinoma in adults with chronic liver disease

Nadarević

Giljača

Colli

et al. 2021

Cochrane Database of Systematic Reviews

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Performance of imaging modalities in diagnosis of liver metastases from colorectal cancer: A systematic review and meta‐analysis

Floriani

Torri

Rulli

et al. 2009

Magnetic Resonance Imaging

238

131

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Surgery of liver metastases can be effective, and the appropriate selection of surgical candidates relies first on imaging. Different techniques are available, but information on their relative performance is unclear. The aim of this overview is to assess the imaging modality performance in the diagnosis of colorectal cancer (CRC) liver metastases. MEDLINE and EMBASE were searched for articles published from January 2000 to August 2008. Eligible trials had to be conducted on patients with diagnosis/suspicion of CRC liver metastases, comparing more than two modalities among MRI, computed tomography (CT), positron emission tomography using fluoro-18-deoxyglucose (FDG-PET), ultrasonography (US). Pooled estimates of sensitivity, specificity were calculated and pairwise comparisons were performed. Of 6030 screened articles, 25 were eligible. Sensitivity and specificity on a per-patient basis for US, CT, MRI, and FDG-PET were 63.0% and 97.6%, 74.8% and 95.6%, 81.1% and 97.2, and 93.8% and 98.7%, respectively. On a per-lesion basis, sensitivity was 86.3%, 82.6%, 86.3%, and 86.0%, respectively. Specificity was reported in few studies. MRI showed a better sensitivity than CT in per-patient (odds ratio [OR]: 0.69; 95% confidence interval [CI]: 0.47-0.99; P ¼ 0.05) and in per-lesion analysis (OR: 0.66; 95% CI: 0.55-0.80; P < 0.0001). In per-lesion analysis, the difference was higher when liver-specific contrast agents were administered. Available evidence supports the MRI use for the detection of CRC liver metastases. SURGICAL TREATMENT OF colorectal cancer (CRC) liver metastases is the only treatment associated with demonstrated long-term survival (1). Patients with untreated but potentially resectable metastases show a median survival of 6 to 12 months (2), while 5-year survival rate of 45-60% can be achieved in appropriate selected patients (3) and this selection relies first on imaging. Although in the past 20 years the role of diagnostic imaging has gained an increasing importance, due to a rapid improvement both in imaging technology and in its clinical application, no consensus has yet emerged on the optimal imaging strategy for the preoperative staging of patients with CRC liver metastases (3). Moreover, after preoperative imaging, intraoperative ultrasonography (IOUS) has been reported to identify at least one additional lesion in 10-12% of cases (4). These data indicate that intensive efforts should be used to improve staging to avoid unnecessary laparotomy and nontherapeutic resection procedures, especially because nowadays resection of liver metastases is pursued with increasing aggressiveness.The diagnostic value of ultrasound with contrast agents, multi-detector computed tomography (MDCT), and MRI with extra-cellular contrast media (ECCM) and liver-specific contrast media (LSCM) is debated. Nowadays MDCT is the mainstay of staging and follow-up of these patients, because it provides good coverage of the liver and the complete abdomen and chest in one session. MRI has been shown to be also useful in the preope...

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Dignitätsbeurteilung fokaler Leberläsionen mit der kontrastverstärkten MRT mit SHU 555 A im Vergleich zur nativen MRT und zur Mehrzeilen-Detektor-Spiral-CT

Abstract: Contrast-enhanced MRI with SHU 555 A has the ability to improve the differential diagnosis of focal liver tumors compared with unenhanced MRI and multislice spiral CT.

Cited by 5 publications

References 8 publications

Evidenzbasierte Radiologie: Ein neuer Ansatz zur Bewertung von klinisch angewandter radiologischer Diagnostik und Therapie

Evidenzbasierte Radiologie: Ein neuer Ansatz zur Bewertung von klinisch angewandter radiologischer Diagnostik und Therapie

Computed tomography for the diagnosis of hepatocellular carcinoma in adults with chronic liver disease

Performance of imaging modalities in diagnosis of liver metastases from colorectal cancer: A systematic review and meta‐analysis

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