Dihydrofurocoumarin glucosides from Angelica archangelica and Angelica silvestris

Stereoselective Synthesis of <i>cis</i>-Substituted-3’-anilino-2’, 3’-dihydro-4-2’-benzo[<i>b</i>]furanylcoumarins via Intramolecular Aldol Reactions

“…The dihydrobenzofuranols has recently received considerable attention since they have been shown to possess antimicrobial activity [7]. Some of the structurally similar compounds 1 [8][9][10][11][12] used as drugs for the treatment of vitiligo and are claimed to be potent coronary vasodilatators, and plant growth regulating substance.…”

Bisxanthones from Hypericum japonicum: Inhibitors of PAF-Induced Hypotension*

“…Wu et al had determined the relative configuration between H-2¢¢ and H-3¢¢ to be cis depending on their coupling constant (J = 6.5 Hz). The coupling constant of 1 between H-2¢¢ and H-3¢¢ was J = 8.3 Hz, which indicated the trans-configuration [15]. This trans-configuration of 1 was also supported by observing the NOE between 4¢¢-methyl protons and H-3¢¢ at d = 6.12.…”

Chemical studies on the root of Heracleum candicans Wall. (Part 3)

“…In our previous studies, we reported the isolation and structure elucidation of nine coumarin derivatives [2,3], in addition two known polyacetylenes, two known phenylpropanoids, and 22 known coumarins; however, the chemical constituents of this plant have not yet been investigated thoroughly. Continued investigation into coumarin components resulted in the isolation of two ester coumarins candinols B and C (1 and 2) and three furanocoumarin dimers candibirins F-H (3)(4)(5) in addition to three known coumarins, 1 0 -O-b-D-glucopyranosyl-(2S,3R)-3-hydroxymarmesin (6) [4], 13-O-[b-D-apiofuranosyl-(1 ? 6)-b-D-glucopyranosyl]-heraclenol (7) [5], rivulotririn A (8) [6] by repeated chromatographic separation of this natural medicine.…”