Dihydropyridine calcium channel blockers in the treatment of arterial hypertension: efficacy and safety of felodipine

Остроумова, О Д; Смолярчук, Е. А.; Kopchenov, I. I.

doi:10.26442/2075-1753_2016.5.23-29

Cited by 2 publications

(2 citation statements)

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“…Due to the lack of clear scientifically grounded recommendations on medication-assisted treatment of various types of AH, doctors in practical healthcare are forced to administer treatment intuitively, based on their personal experience. Patients do not take medicine on regular basis, therefore their ABP can hardly be controlled and remains elevated 1,2,3,4 . Therefore, the search for an optimal individualized approach to the treatment of AH patients with hypotensive drugs is considered to be an urgent issue.…”

Section: Introductionmentioning

confidence: 99%

“…At present, a great selection of hypotensive drugs is available with the drugs of calcium channel blocker class being of particular interest 4,9,10,11 . A number of research works demonstrate the ability of some drugs of this class to prevent the development of cardiovascular complications 1,12,13,3 . At the present time, extended-release diltiazem is widely used and highly researched from the perspective of evidence-based medicine 13 .…”

Section: Introductionmentioning

confidence: 99%

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Influence of altiazem pp-180 on hemodynamic parameters in arterial hypertension patients under outpatient conditions

Zhakiyeva

Tulegenova

Ibragimova

et al. 2018

Bangladesh J Med Sci

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Background: The objective is to study the time-dependent hemodynamic effects of altiazem PP-180 and the blood circulation parameters in patients with arterial hypertension of the II degree in outpatient polyclinic conditions.Methods: The study included 78 patients with essential II grade AH aged 42 to 73 years (mean age of 57.65 ± 0.6). Among them were 28 men and 50 women. The duration of the disease ranged from 4 to 23 years (an average of 9.2 ± 0.12). All the groups involved in the research were divided into two subgroups: the main group and the control group. The control group included 30 patients, who took A-180 once a day at non-fixed hours. The main group included 48 patients, who were divided into random subgroups depending on the time they took A-180 once a day. Within 3 days prior to treatment and during the 10-day treatment course, the medical staff measured all the pateints’ heart rate and blood pressure by NC Korotkoff every 3 hours, 6 times a day. The patients’ heart rate and blood pressure were alternatively self-measured. Prior to treatment and at the end of the 10-day course of therapy with altiazem PP-180, all the patients involved in the research underwent ECG examination and echocardiography on the Aloka machine (Japan).Results: The most favorable hemodynamic support for the hypotensive effect of altiazem PP-180 was observed when patients took it at 7 a.m., 10 a.m. and 10 p.m. in their normal mode of work and rest. When patients took altiazem PP-180 at 1 p.m, 4 p.m. and 7 p.m., its hypotensive effect was due to less favorable hemodynamic support.Conclusions: When taken at different hours of the day - both fixed and non-fixed hours - altiazem PP-180 caused a distinct hypotensive effect in patients with the II degree AH in outpatient polyclinic conditions.Bangladesh Journal of Medical Science Vol.17(3) 2018 p.360-368

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Influence of altiazem pp-180 on hemodynamic parameters in arterial hypertension patients under outpatient conditions

Zhakiyeva

Tulegenova

Ibragimova

et al. 2018

Bangladesh J Med Sci

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Optimisation of T2 and T2* sequences in MRI for better quantification of iron on transfused dependent sickle cell patients

Ahmed¹,

Baldo²,

Sulieman

et al. 2021

Sci Rep

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This work aimed to investigate the effect of different shim techniques, voxel sizes, and repetition time (TR) on using theT2 and T2* sequences to determine their optimum settings to investigate the quantification of iron in transfused dependent sickle cell patients. The effect of each of these parameters was investigated on phantoms of different Gadolinium (Gd) concentrations, on 10 volunteers and 25 patients using a1 5T MRI Philips scanner. No significant difference between the three shim techniques was noticed in either T2 or T2* sequence measurements. Pixel sizes of 1 × 1 and 2 × 2 mm provided optimum results for T2 measurements. At 1 × 1 mm pixel size the T2* measurements experienced less error in measurements than the size of 2.5 × 2.5 mm used in the literature. Even though the slice thickness variation did not provide any changes in T2 measurements, the 12 mm provided optimum T2* measurements. TR variation did not yield significant changes on either T2 or T2* measurements. These results indicate that both T2 and T2* sequences can be further improved by providing more reliable measurements and reducing acquisition time.

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Dihydropyridine calcium channel blockers in the treatment of arterial hypertension: efficacy and safety of felodipine

Cited by 2 publications

References 0 publications

Influence of altiazem pp-180 on hemodynamic parameters in arterial hypertension patients under outpatient conditions

Influence of altiazem pp-180 on hemodynamic parameters in arterial hypertension patients under outpatient conditions

Optimisation of T2 and T2* sequences in MRI for better quantification of iron on transfused dependent sickle cell patients

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