Bowing is an uncommon pathology that can affect marble stone cladding of building façades, causing a large permanent deflection and the degradation of the flexural and anchoring strength of the stone slabs, which can lead to the cladding falling from the façades. Moreover, the combination of bowing with wind pressure effects on the building façades can increase the risk of fracture and collapse of the stone slabs, especially if this combination is not properly evaluated during design. Motivated by a case study, this work describes a stability evaluation of a 15-year-old building façade coated with marble stone cladding affected by bowing and subjected to wind pressures. This evaluation was focused on the stone slabs, and was performed through finite element model (FEM) numerical simulations of these slabs submitted to wind pressures and through lab tests using samples of stone slabs removed from the building façade. The results obtained demonstrated stability problems on the stone slabs caused by wind pressure-induced stresses combined with the loss of strength due to aging and bowing effects, especially for slabs with larger dimensions.